Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1937 | TNBC | Basal A | AG1478 | EGFR | ErbB | 0.00213 | uM | 7834.016 | 0.9922 | 0.9924 | 2.0442 | |
| HCC1937 | TNBC | Basal A | AG1478 | EGFR | ErbB | 0.0107 | uM | 7834.016 | 1.0109 | 1.0107 | 2.0442 | |
| HCC1937 | TNBC | Basal A | AG1478 | EGFR | ErbB | 0.0533 | uM | 7834.016 | 0.9000 | 0.8995 | 2.0442 | |
| HCC1937 | TNBC | Basal A | AG1478 | EGFR | ErbB | 0.267 | uM | 7834.016 | 0.8558 | 0.8534 | 2.0442 | |
| HCC1937 | TNBC | Basal A | AG1478 | EGFR | ErbB | 1.33 | uM | 7834.016 | 0.7871 | 0.7790 | 2.0442 | |
| HCC1937 | TNBC | Basal A | AG1478 | EGFR | ErbB | 6.67 | uM | 7834.016 | 0.8139 | 0.8084 | 2.0442 | |
| HCC1937 | TNBC | Basal A | AG1478 | EGFR | ErbB | 33.3 | uM | 7834.016 | 0.3101 | 0.1280 | 2.0442 | |
| HCC1937 | TNBC | Basal A | AG1478 | EGFR | ErbB | 167 | uM | 7834.016 | 0.0472 | -0.5508 | 2.0442 | |
| HCC1954 | HER2amp | Basal A | AG1478 | EGFR | ErbB | 0.000427 | uM | 7836.016 | 1.0279 | 1.0354 | 1.5669 | |
| HCC1954 | HER2amp | Basal A | AG1478 | EGFR | ErbB | 0.00213 | uM | 7836.016 | 0.9764 | 0.9698 | 1.5669 | |
| HCC1954 | HER2amp | Basal A | AG1478 | EGFR | ErbB | 0.0107 | uM | 7836.016 | 1.0204 | 1.0259 | 1.5669 | |
| HCC1954 | HER2amp | Basal A | AG1478 | EGFR | ErbB | 0.0533 | uM | 7836.016 | 0.8867 | 0.8523 | 1.5669 | |
| HCC1954 | HER2amp | Basal A | AG1478 | EGFR | ErbB | 0.267 | uM | 7836.016 | 0.9477 | 0.9326 | 1.5669 | |
| HCC1954 | HER2amp | Basal A | AG1478 | EGFR | ErbB | 1.33 | uM | 7836.016 | 0.6836 | 0.5690 | 1.5669 | |
| HCC1954 | HER2amp | Basal A | AG1478 | EGFR | ErbB | 6.67 | uM | 7836.016 | 0.5463 | 0.3597 | 1.5669 | |
| HCC1954 | HER2amp | Basal A | AG1478 | EGFR | ErbB | 33.3 | uM | 7836.016 | 0.4266 | 0.1612 | 1.5669 | |
| HCC1954 | HER2amp | Basal A | AG1478 | EGFR | ErbB | 167 | uM | 7836.016 | 0.1626 | -0.3725 | 1.5669 | |
| HCC1954 | HER2amp | Basal A | AG1478 | EGFR | ErbB | 0.000427 | uM | 7837.016 | 0.8816 | 0.8653 | 1.8067 | |
| HCC1954 | HER2amp | Basal A | AG1478 | EGFR | ErbB | 0.00213 | uM | 7837.016 | 0.7775 | 0.7399 | 1.8067 | |
| HCC1954 | HER2amp | Basal A | AG1478 | EGFR | ErbB | 0.0107 | uM | 7837.016 | 0.9765 | 0.9738 | 1.8067 | |
| HCC1954 | HER2amp | Basal A | AG1478 | EGFR | ErbB | 0.0533 | uM | 7837.016 | 0.7324 | 0.6833 | 1.8067 | |
| HCC1954 | HER2amp | Basal A | AG1478 | EGFR | ErbB | 0.267 | uM | 7837.016 | 0.7524 | 0.7086 | 1.8067 | |
| HCC1954 | HER2amp | Basal A | AG1478 | EGFR | ErbB | 1.33 | uM | 7837.016 | 0.4614 | 0.3034 | 1.8067 | |
| HCC1954 | HER2amp | Basal A | AG1478 | EGFR | ErbB | 6.67 | uM | 7837.016 | 0.4119 | 0.2242 | 1.8067 | |
| HCC1954 | HER2amp | Basal A | AG1478 | EGFR | ErbB | 33.3 | uM | 7837.016 | 0.7005 | 0.6424 | 1.8067 |