Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ZR-75-1 | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.0403 | uM | 9958.021 | 1.0157 | 1.0617 | 0.5129 | |
| ZR-75-1 | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.201 | uM | 9958.021 | 1.0171 | 1.0671 | 0.5129 | |
| ZR-75-1 | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 1.01 | uM | 9958.021 | 0.9964 | 0.9862 | 0.5129 | |
| ZR-75-1 | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 5.03 | uM | 9958.021 | 0.6850 | -0.0436 | 0.5129 | |
| ZR-75-1 | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 25.2 | uM | 9958.021 | 0.6097 | -0.2378 | 0.5129 | |
| ZR-75-1 | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 126 | uM | 9958.021 | 0.1080 | -0.9739 | 0.5129 | |
| ZR-75-1 | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 629 | uM | 9958.021 | 0.0134 | -0.9996 | 0.5129 | |
| ZR75B | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00161 | uM | 9972.011 | 1.2785 | 1.5952 | 0.9432 | |
| ZR75B | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00805 | uM | 9972.011 | 1.2073 | 1.4421 | 0.9432 | |
| ZR75B | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.0403 | uM | 9972.011 | 1.2729 | 1.5830 | 0.9432 | |
| ZR75B | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.201 | uM | 9972.011 | 1.0863 | 1.1834 | 0.9432 | |
| ZR75B | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 1.01 | uM | 9972.011 | 0.7727 | 0.5216 | 0.9432 | |
| ZR75B | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 5.03 | uM | 9972.011 | 0.6336 | 0.2328 | 0.9432 | |
| ZR75B | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 25.2 | uM | 9972.011 | 0.6018 | 0.1673 | 0.9432 | |
| ZR75B | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 126 | uM | 9972.011 | 0.1647 | -0.7045 | 0.9432 | |
| ZR75B | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 629 | uM | 9972.011 | 0.0788 | -0.8648 | 0.9432 | |
| ZR75B | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00161 | uM | 9997.011 | 0.9833 | 0.9684 | 1.0551 | |
| ZR75B | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00805 | uM | 9997.011 | 1.0570 | 1.1079 | 1.0551 | |
| ZR75B | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.0403 | uM | 9997.011 | 1.0486 | 1.0921 | 1.0551 | |
| ZR75B | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.201 | uM | 9997.011 | 1.0088 | 1.0166 | 1.0551 | |
| ZR75B | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 1.01 | uM | 9997.011 | 0.7112 | 0.4480 | 1.0551 | |
| ZR75B | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 5.03 | uM | 9997.011 | 0.6091 | 0.2502 | 1.0551 | |
| ZR75B | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 25.2 | uM | 9997.011 | 0.5564 | 0.1473 | 1.0551 | |
| ZR75B | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 126 | uM | 9997.011 | 0.2601 | -0.4419 | 1.0551 | |
| ZR75B | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 629 | uM | 9997.011 | 0.1181 | -0.7360 | 1.0551 |