Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM159PT | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 5.03 | uM | 9844.021 | 0.3660 | 0.3355 | 2.4889 | |
| SUM159PT | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 25.2 | uM | 9844.021 | 0.1715 | -0.0152 | 2.4889 | |
| SUM159PT | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 126 | uM | 9844.021 | 0.0427 | -0.4369 | 2.4889 | |
| SUM159PT | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 629 | uM | 9844.021 | 0.0189 | -0.5941 | 2.4889 | |
| SUM185PE | TNBC | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00161 | uM | 7921.011 | 1.0086 | 1.0254 | 0.6757 | |
| SUM185PE | TNBC | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00805 | uM | 7921.011 | 0.9912 | 0.9741 | 0.6757 | |
| SUM185PE | TNBC | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.0403 | uM | 7921.011 | 1.0036 | 1.0106 | 0.6757 | |
| SUM185PE | TNBC | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.201 | uM | 7921.011 | 1.0064 | 1.0191 | 0.6757 | |
| SUM185PE | TNBC | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 1.01 | uM | 7921.011 | 1.0085 | 1.0252 | 0.6757 | |
| SUM185PE | TNBC | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 5.03 | uM | 7921.011 | 0.9271 | 0.7880 | 0.6757 | |
| SUM185PE | TNBC | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 25.2 | uM | 7921.011 | 0.9268 | 0.7872 | 0.6757 | |
| SUM185PE | TNBC | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 126 | uM | 7921.011 | 0.0842 | -0.9487 | 0.6757 | |
| SUM185PE | TNBC | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 629 | uM | 7921.011 | 0.0427 | -0.9812 | 0.6757 | |
| SUM185PE | TNBC | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00161 | uM | 10146.12 | 1.0864 | 1.1669 | 1.0341 | |
| SUM185PE | TNBC | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00805 | uM | 10146.12 | 0.9982 | 0.9965 | 1.0341 | |
| SUM185PE | TNBC | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.0403 | uM | 10146.12 | 1.0308 | 1.0596 | 1.0341 | |
| SUM185PE | TNBC | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.201 | uM | 10146.12 | 0.9064 | 0.8187 | 1.0341 | |
| SUM185PE | TNBC | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 1.01 | uM | 10146.12 | 0.9723 | 0.9464 | 1.0341 | |
| SUM185PE | TNBC | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 5.03 | uM | 10146.12 | 0.9353 | 0.8748 | 1.0341 | |
| SUM185PE | TNBC | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 25.2 | uM | 10146.12 | 0.8932 | 0.7931 | 1.0341 | |
| SUM185PE | TNBC | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 126 | uM | 10146.12 | 0.1347 | -0.7121 | 1.0341 | |
| SUM185PE | TNBC | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 629 | uM | 10146.12 | 0.0129 | -0.9703 | 1.0341 | |
| SUM229PE | TNBC | - | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00161 | uM | 9860.011 | 1.1741 | 1.2322 | 1.4618 | |
| SUM229PE | TNBC | - | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00805 | uM | 9860.011 | 1.1327 | 1.1780 | 1.4618 | |
| SUM229PE | TNBC | - | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.0403 | uM | 9860.011 | 1.1655 | 1.2209 | 1.4618 |