Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset - HMS LINCS Database

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)

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Small molecules	Cells	Antibodies

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Cell	Clinical Subtype	Transcriptional Subtype	Small Molecule	Perturbagen Target	Perturbagen Class	Perturbagen Concentration	Perturbagen Conc Unit	Biological Replicate ID	Relative Cell Count	Normalized Growth Rate Inhibition Value	Nominal Division Rate
MDA-MB-175-VII	HR+	Luminal	Nilotinib	ABL	nRTK	0.0128	uM	10642.145	1.0251	1.1453	0.3537
MDA-MB-175-VII	HR+	Luminal	Nilotinib	ABL	nRTK	0.064	uM	10642.145	1.0542	1.3220	0.3537
MDA-MB-175-VII	HR+	Luminal	Nilotinib	ABL	nRTK	0.32	uM	10642.145	1.0060	1.0341	0.3537
MDA-MB-175-VII	HR+	Luminal	Nilotinib	ABL	nRTK	1.6	uM	10642.145	0.9765	0.8698	0.3537
MDA-MB-175-VII	HR+	Luminal	Nilotinib	ABL	nRTK	8	uM	10642.145	0.8857	0.4192	0.3537
MDA-MB-175-VII	HR+	Luminal	Nilotinib	ABL	nRTK	40	uM	10642.145	0.6623	-0.3759	0.3537
MDA-MB-175-VII	HR+	Luminal	Nilotinib	ABL	nRTK	200	uM	10642.145	0.8694	0.3463	0.3537
MDA-MB-175-VII	HR+	Luminal	Nilotinib	ABL	nRTK	0.000512	uM	10818.145	0.9939	0.9737	0.4621
MDA-MB-175-VII	HR+	Luminal	Nilotinib	ABL	nRTK	0.00256	uM	10818.145	0.9396	0.7476	0.4621
MDA-MB-175-VII	HR+	Luminal	Nilotinib	ABL	nRTK	0.0128	uM	10818.145	0.9955	0.9805	0.4621
MDA-MB-175-VII	HR+	Luminal	Nilotinib	ABL	nRTK	0.064	uM	10818.145	1.0141	1.0614	0.4621
MDA-MB-175-VII	HR+	Luminal	Nilotinib	ABL	nRTK	0.32	uM	10818.145	0.9911	0.9617	0.4621
MDA-MB-175-VII	HR+	Luminal	Nilotinib	ABL	nRTK	1.6	uM	10818.145	0.9460	0.7734	0.4621
MDA-MB-175-VII	HR+	Luminal	Nilotinib	ABL	nRTK	8	uM	10818.145	0.9185	0.6638	0.4621
MDA-MB-175-VII	HR+	Luminal	Nilotinib	ABL	nRTK	40	uM	10818.145	0.9329	0.7209	0.4621
MDA-MB-175-VII	HR+	Luminal	Nilotinib	ABL	nRTK	200	uM	10818.145	0.9266	0.6960	0.4621
MDA-MB-175-VII	HR+	Luminal	Nilotinib	ABL	nRTK	0.000512	uM	12126.145	1.0430	1.1341	0.6493
MDA-MB-175-VII	HR+	Luminal	Nilotinib	ABL	nRTK	0.00256	uM	12126.145	0.9160	0.7472	0.6493
MDA-MB-175-VII	HR+	Luminal	Nilotinib	ABL	nRTK	0.0128	uM	12126.145	1.0114	1.0351	0.6493
MDA-MB-175-VII	HR+	Luminal	Nilotinib	ABL	nRTK	0.064	uM	12126.145	0.9367	0.8085	0.6493
MDA-MB-175-VII	HR+	Luminal	Nilotinib	ABL	nRTK	0.32	uM	12126.145	0.9005	0.7019	0.6493
MDA-MB-175-VII	HR+	Luminal	Nilotinib	ABL	nRTK	1.6	uM	12126.145	0.9894	0.9675	0.6493
MDA-MB-175-VII	HR+	Luminal	Nilotinib	ABL	nRTK	8	uM	12126.145	0.9425	0.8257	0.6493
MDA-MB-175-VII	HR+	Luminal	Nilotinib	ABL	nRTK	40	uM	12126.145	1.0470	1.1466	0.6493
MDA-MB-175-VII	HR+	Luminal	Nilotinib	ABL	nRTK	200	uM	12126.145	0.9393	0.8161	0.6493

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HMS LINCS Project

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)