Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UACC-812 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 11938.145 | 0.8902 | 0.6963 | 0.7062 | |
| UACC-812 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.107 | uM | 11938.145 | 0.8718 | 0.6470 | 0.7062 | |
| UACC-812 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.107 | uM | 11938.145 | 0.8718 | 0.6470 | 0.7062 | |
| UACC-812 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.533 | uM | 11938.145 | 0.3170 | -0.6069 | 0.7062 | |
| UACC-812 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.533 | uM | 11938.145 | 0.3170 | -0.6069 | 0.7062 | |
| UACC-812 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 2.67 | uM | 11938.145 | 0.0137 | -0.9954 | 0.7062 | |
| UACC-812 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 2.67 | uM | 11938.145 | 0.0137 | -0.9954 | 0.7062 | |
| UACC-812 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 13.3 | uM | 11938.145 | 0.0128 | -0.9959 | 0.7062 | |
| UACC-812 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 13.3 | uM | 11938.145 | 0.0128 | -0.9959 | 0.7062 | |
| UACC-812 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 66.7 | uM | 11938.145 | 0.0102 | -0.9970 | 0.7062 | |
| UACC-812 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 66.7 | uM | 11938.145 | 0.0102 | -0.9970 | 0.7062 | |
| UACC-812 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 14227.189 | 0.9292 | 0.8878 | 1.2712 | |
| UACC-812 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 14227.189 | 0.9292 | 0.8878 | 1.2712 | |
| UACC-812 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 14227.189 | 0.9148 | 0.8646 | 1.2712 | |
| UACC-812 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 14227.189 | 0.9148 | 0.8646 | 1.2712 | |
| UACC-812 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 14227.189 | 0.9526 | 0.9251 | 1.2712 | |
| UACC-812 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 14227.189 | 0.9526 | 0.9251 | 1.2712 | |
| UACC-812 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 14227.189 | 0.9678 | 0.9492 | 1.2712 | |
| UACC-812 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 14227.189 | 0.9678 | 0.9492 | 1.2712 | |
| UACC-812 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.107 | uM | 14227.189 | 0.9195 | 0.8723 | 1.2712 | |
| UACC-812 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.107 | uM | 14227.189 | 0.9195 | 0.8723 | 1.2712 | |
| UACC-812 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.533 | uM | 14227.189 | 0.5207 | 0.1970 | 1.2712 | |
| UACC-812 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.533 | uM | 14227.189 | 0.5207 | 0.1970 | 1.2712 | |
| UACC-812 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 2.67 | uM | 14227.189 | 0.3634 | -0.0980 | 1.2712 | |
| UACC-812 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 2.67 | uM | 14227.189 | 0.3634 | -0.0980 | 1.2712 |