Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM225CWN | HER2amp | Basal A | MG-132 | Proteasome | Proteasome | 0.107 | uM | 12098.145 | 0.5859 | 0.1570 | 0.9769 | |
| SUM225CWN | HER2amp | Basal A | MG-132 | Proteasome | Proteasome | 0.533 | uM | 12098.145 | 0.3450 | -0.3271 | 0.9769 | |
| SUM225CWN | HER2amp | Basal A | MG-132 | Proteasome | Proteasome | 0.533 | uM | 12098.145 | 0.3450 | -0.3271 | 0.9769 | |
| SUM225CWN | HER2amp | Basal A | MG-132 | Proteasome | Proteasome | 2.67 | uM | 12098.145 | 0.2168 | -0.5818 | 0.9769 | |
| SUM225CWN | HER2amp | Basal A | MG-132 | Proteasome | Proteasome | 2.67 | uM | 12098.145 | 0.2168 | -0.5818 | 0.9769 | |
| SUM225CWN | HER2amp | Basal A | MG-132 | Proteasome | Proteasome | 13.3 | uM | 12098.145 | 0.1596 | -0.6944 | 0.9769 | |
| SUM225CWN | HER2amp | Basal A | MG-132 | Proteasome | Proteasome | 13.3 | uM | 12098.145 | 0.1596 | -0.6944 | 0.9769 | |
| SUM225CWN | HER2amp | Basal A | MG-132 | Proteasome | Proteasome | 66.7 | uM | 12098.145 | 0.1770 | -0.6603 | 0.9769 | |
| SUM225CWN | HER2amp | Basal A | MG-132 | Proteasome | Proteasome | 66.7 | uM | 12098.145 | 0.1770 | -0.6603 | 0.9769 | |
| SUM229PE | TNBC | - | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 11058.145 | 0.9875 | 0.9886 | 2.2039 | |
| SUM229PE | TNBC | - | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 11058.145 | 0.9875 | 0.9886 | 2.2039 | |
| SUM229PE | TNBC | - | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 11058.145 | 1.0258 | 1.0233 | 2.2039 | |
| SUM229PE | TNBC | - | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 11058.145 | 1.0258 | 1.0233 | 2.2039 | |
| SUM229PE | TNBC | - | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 11058.145 | 0.9857 | 0.9869 | 2.2039 | |
| SUM229PE | TNBC | - | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 11058.145 | 0.9857 | 0.9869 | 2.2039 | |
| SUM229PE | TNBC | - | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 11058.145 | 1.0514 | 1.0460 | 2.2039 | |
| SUM229PE | TNBC | - | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 11058.145 | 1.0514 | 1.0460 | 2.2039 | |
| SUM229PE | TNBC | - | MG-132 | Proteasome | Proteasome | 0.107 | uM | 11058.145 | 0.5506 | 0.5256 | 2.2039 | |
| SUM229PE | TNBC | - | MG-132 | Proteasome | Proteasome | 0.107 | uM | 11058.145 | 0.5506 | 0.5256 | 2.2039 | |
| SUM229PE | TNBC | - | MG-132 | Proteasome | Proteasome | 0.533 | uM | 11058.145 | 0.0412 | -0.5297 | 2.2039 | |
| SUM229PE | TNBC | - | MG-132 | Proteasome | Proteasome | 0.533 | uM | 11058.145 | 0.0412 | -0.5297 | 2.2039 | |
| SUM229PE | TNBC | - | MG-132 | Proteasome | Proteasome | 2.67 | uM | 11058.145 | 0.0266 | -0.6140 | 2.2039 | |
| SUM229PE | TNBC | - | MG-132 | Proteasome | Proteasome | 2.67 | uM | 11058.145 | 0.0266 | -0.6140 | 2.2039 | |
| SUM229PE | TNBC | - | MG-132 | Proteasome | Proteasome | 13.3 | uM | 11058.145 | 0.0267 | -0.6137 | 2.2039 | |
| SUM229PE | TNBC | - | MG-132 | Proteasome | Proteasome | 13.3 | uM | 11058.145 | 0.0267 | -0.6137 | 2.2039 |