Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.533 | uM | 14221.189 | 0.3549 | 0.0268 | 1.5537 | |
| SK-BR-3 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 2.67 | uM | 14221.189 | 0.0513 | -0.7043 | 1.5537 | |
| SK-BR-3 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 2.67 | uM | 14221.189 | 0.0513 | -0.7043 | 1.5537 | |
| SK-BR-3 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 13.3 | uM | 14221.189 | 0.2264 | -0.2311 | 1.5537 | |
| SK-BR-3 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 13.3 | uM | 14221.189 | 0.2264 | -0.2311 | 1.5537 | |
| SK-BR-3 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 66.7 | uM | 14221.189 | 0.3716 | 0.0576 | 1.5537 | |
| SK-BR-3 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 66.7 | uM | 14221.189 | 0.3716 | 0.0576 | 1.5537 | |
| SUM1315MO2 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 10875.145 | 1.0197 | 1.0517 | 0.7643 | |
| SUM1315MO2 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 10875.145 | 1.0197 | 1.0517 | 0.7643 | |
| SUM1315MO2 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 10875.145 | 1.0125 | 1.0328 | 0.7643 | |
| SUM1315MO2 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 10875.145 | 1.0125 | 1.0328 | 0.7643 | |
| SUM1315MO2 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 10875.145 | 1.0078 | 1.0203 | 0.7643 | |
| SUM1315MO2 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 10875.145 | 1.0078 | 1.0203 | 0.7643 | |
| SUM1315MO2 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 10875.145 | 1.0144 | 1.0378 | 0.7643 | |
| SUM1315MO2 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 10875.145 | 1.0144 | 1.0378 | 0.7643 | |
| SUM1315MO2 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.107 | uM | 10875.145 | 0.7865 | 0.4606 | 0.7643 | |
| SUM1315MO2 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.107 | uM | 10875.145 | 0.7865 | 0.4606 | 0.7643 | |
| SUM1315MO2 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.533 | uM | 10875.145 | 0.2552 | -0.6651 | 0.7643 | |
| SUM1315MO2 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.533 | uM | 10875.145 | 0.2552 | -0.6651 | 0.7643 | |
| SUM1315MO2 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 2.67 | uM | 10875.145 | 0.0186 | -0.9891 | 0.7643 | |
| SUM1315MO2 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 2.67 | uM | 10875.145 | 0.0186 | -0.9891 | 0.7643 | |
| SUM1315MO2 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 13.3 | uM | 10875.145 | 0.0158 | -0.9912 | 0.7643 | |
| SUM1315MO2 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 13.3 | uM | 10875.145 | 0.0158 | -0.9912 | 0.7643 | |
| SUM1315MO2 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 66.7 | uM | 10875.145 | 0.0150 | -0.9918 | 0.7643 | |
| SUM1315MO2 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 66.7 | uM | 10875.145 | 0.0150 | -0.9918 | 0.7643 |