Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MX1 | Unknown | Unknown | MG-132 | Proteasome | Proteasome | 13.3 | uM | 14278.189 | 0.0177 | -0.9921 | 0.7296 | |
| MX1 | Unknown | Unknown | MG-132 | Proteasome | Proteasome | 66.7 | uM | 14278.189 | 0.9768 | 0.9366 | 0.7296 | |
| MX1 | Unknown | Unknown | MG-132 | Proteasome | Proteasome | 66.7 | uM | 14278.189 | 0.9768 | 0.9366 | 0.7296 | |
| MX1 | Unknown | Unknown | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 14649.189 | 1.0250 | 1.0887 | 0.5692 | |
| MX1 | Unknown | Unknown | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 14649.189 | 1.0250 | 1.0887 | 0.5692 | |
| MX1 | Unknown | Unknown | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 14649.189 | 1.0247 | 1.0876 | 0.5692 | |
| MX1 | Unknown | Unknown | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 14649.189 | 1.0247 | 1.0876 | 0.5692 | |
| MX1 | Unknown | Unknown | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 14649.189 | 1.0334 | 1.1188 | 0.5692 | |
| MX1 | Unknown | Unknown | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 14649.189 | 1.0334 | 1.1188 | 0.5692 | |
| MX1 | Unknown | Unknown | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 14649.189 | 0.9882 | 0.9586 | 0.5692 | |
| MX1 | Unknown | Unknown | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 14649.189 | 0.9882 | 0.9586 | 0.5692 | |
| MX1 | Unknown | Unknown | MG-132 | Proteasome | Proteasome | 0.107 | uM | 14649.189 | 1.0156 | 1.0550 | 0.5692 | |
| MX1 | Unknown | Unknown | MG-132 | Proteasome | Proteasome | 0.107 | uM | 14649.189 | 1.0156 | 1.0550 | 0.5692 | |
| MX1 | Unknown | Unknown | MG-132 | Proteasome | Proteasome | 0.533 | uM | 14649.189 | 0.5211 | -0.3637 | 0.5692 | |
| MX1 | Unknown | Unknown | MG-132 | Proteasome | Proteasome | 0.533 | uM | 14649.189 | 0.5211 | -0.3637 | 0.5692 | |
| MX1 | Unknown | Unknown | MG-132 | Proteasome | Proteasome | 2.67 | uM | 14649.189 | 0.0325 | -0.9952 | 0.5692 | |
| MX1 | Unknown | Unknown | MG-132 | Proteasome | Proteasome | 2.67 | uM | 14649.189 | 0.0325 | -0.9952 | 0.5692 | |
| MX1 | Unknown | Unknown | MG-132 | Proteasome | Proteasome | 13.3 | uM | 14649.189 | 0.0120 | -0.9992 | 0.5692 | |
| MX1 | Unknown | Unknown | MG-132 | Proteasome | Proteasome | 13.3 | uM | 14649.189 | 0.0120 | -0.9992 | 0.5692 | |
| MX1 | Unknown | Unknown | MG-132 | Proteasome | Proteasome | 66.7 | uM | 14649.189 | 0.0156 | -0.9987 | 0.5692 | |
| MX1 | Unknown | Unknown | MG-132 | Proteasome | Proteasome | 66.7 | uM | 14649.189 | 0.0156 | -0.9987 | 0.5692 | |
| SK-BR-3 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 11851.145 | 0.9361 | 0.9131 | 1.4873 | |
| SK-BR-3 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 11851.145 | 0.9361 | 0.9131 | 1.4873 | |
| SK-BR-3 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 11851.145 | 1.0379 | 1.0506 | 1.4873 | |
| SK-BR-3 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 11851.145 | 1.0379 | 1.0506 | 1.4873 |