Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 11851.145 | 0.9442 | 0.9243 | 1.4873 | |
| SK-BR-3 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 11851.145 | 0.9442 | 0.9243 | 1.4873 | |
| SK-BR-3 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 11851.145 | 0.9889 | 0.9850 | 1.4873 | |
| SK-BR-3 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 11851.145 | 0.9889 | 0.9850 | 1.4873 | |
| SK-BR-3 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.107 | uM | 11851.145 | 0.9353 | 0.9121 | 1.4873 | |
| SK-BR-3 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.107 | uM | 11851.145 | 0.9353 | 0.9121 | 1.4873 | |
| SK-BR-3 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.533 | uM | 11851.145 | 0.1920 | -0.3405 | 1.4873 | |
| SK-BR-3 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.533 | uM | 11851.145 | 0.1920 | -0.3405 | 1.4873 | |
| SK-BR-3 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 2.67 | uM | 11851.145 | 0.0584 | -0.7037 | 1.4873 | |
| SK-BR-3 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 2.67 | uM | 11851.145 | 0.0584 | -0.7037 | 1.4873 | |
| SK-BR-3 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 13.3 | uM | 11851.145 | 0.0429 | -0.7591 | 1.4873 | |
| SK-BR-3 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 13.3 | uM | 11851.145 | 0.0429 | -0.7591 | 1.4873 | |
| SK-BR-3 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 66.7 | uM | 11851.145 | 0.0464 | -0.7463 | 1.4873 | |
| SK-BR-3 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 66.7 | uM | 11851.145 | 0.0464 | -0.7463 | 1.4873 | |
| SK-BR-3 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 14221.189 | 0.9846 | 0.9801 | 1.5537 | |
| SK-BR-3 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 14221.189 | 0.9846 | 0.9801 | 1.5537 | |
| SK-BR-3 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 14221.189 | 0.9367 | 0.9175 | 1.5537 | |
| SK-BR-3 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 14221.189 | 0.9367 | 0.9175 | 1.5537 | |
| SK-BR-3 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 14221.189 | 0.9987 | 0.9983 | 1.5537 | |
| SK-BR-3 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 14221.189 | 0.9987 | 0.9983 | 1.5537 | |
| SK-BR-3 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 14221.189 | 0.9733 | 0.9655 | 1.5537 | |
| SK-BR-3 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 14221.189 | 0.9733 | 0.9655 | 1.5537 | |
| SK-BR-3 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.107 | uM | 14221.189 | 0.9851 | 0.9807 | 1.5537 | |
| SK-BR-3 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.107 | uM | 14221.189 | 0.9851 | 0.9807 | 1.5537 | |
| SK-BR-3 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.533 | uM | 14221.189 | 0.3549 | 0.0268 | 1.5537 |