Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-453 | TNBC | Luminal | MG-132 | Proteasome | Proteasome | 2.67 | uM | 12414.17 | 0.0164 | -0.9338 | 1.2052 | |
| MDA-MB-453 | TNBC | Luminal | MG-132 | Proteasome | Proteasome | 2.67 | uM | 12414.17 | 0.0164 | -0.9338 | 1.2052 | |
| MDA-MB-453 | TNBC | Luminal | MG-132 | Proteasome | Proteasome | 13.3 | uM | 12414.17 | 0.0153 | -0.9378 | 1.2052 | |
| MDA-MB-453 | TNBC | Luminal | MG-132 | Proteasome | Proteasome | 13.3 | uM | 12414.17 | 0.0153 | -0.9378 | 1.2052 | |
| MDA-MB-453 | TNBC | Luminal | MG-132 | Proteasome | Proteasome | 66.7 | uM | 12414.17 | 0.0137 | -0.9432 | 1.2052 | |
| MDA-MB-453 | TNBC | Luminal | MG-132 | Proteasome | Proteasome | 66.7 | uM | 12414.17 | 0.0137 | -0.9432 | 1.2052 | |
| MDA-MB-453 | TNBC | Luminal | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 14646.189 | 0.8776 | 0.7686 | 1.0620 | |
| MDA-MB-453 | TNBC | Luminal | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 14646.189 | 0.8776 | 0.7686 | 1.0620 | |
| MDA-MB-453 | TNBC | Luminal | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 14646.189 | 0.9134 | 0.8364 | 1.0620 | |
| MDA-MB-453 | TNBC | Luminal | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 14646.189 | 0.9134 | 0.8364 | 1.0620 | |
| MDA-MB-453 | TNBC | Luminal | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 14646.189 | 0.8949 | 0.8014 | 1.0620 | |
| MDA-MB-453 | TNBC | Luminal | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 14646.189 | 0.8949 | 0.8014 | 1.0620 | |
| MDA-MB-453 | TNBC | Luminal | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 14646.189 | 0.9120 | 0.8338 | 1.0620 | |
| MDA-MB-453 | TNBC | Luminal | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 14646.189 | 0.9120 | 0.8338 | 1.0620 | |
| MDA-MB-453 | TNBC | Luminal | MG-132 | Proteasome | Proteasome | 0.107 | uM | 14646.189 | 0.8579 | 0.7313 | 1.0620 | |
| MDA-MB-453 | TNBC | Luminal | MG-132 | Proteasome | Proteasome | 0.107 | uM | 14646.189 | 0.8579 | 0.7313 | 1.0620 | |
| MDA-MB-453 | TNBC | Luminal | MG-132 | Proteasome | Proteasome | 0.533 | uM | 14646.189 | 0.3753 | -0.2052 | 1.0620 | |
| MDA-MB-453 | TNBC | Luminal | MG-132 | Proteasome | Proteasome | 0.533 | uM | 14646.189 | 0.3753 | -0.2052 | 1.0620 | |
| MDA-MB-453 | TNBC | Luminal | MG-132 | Proteasome | Proteasome | 2.67 | uM | 14646.189 | 0.2175 | -0.5245 | 1.0620 | |
| MDA-MB-453 | TNBC | Luminal | MG-132 | Proteasome | Proteasome | 2.67 | uM | 14646.189 | 0.2175 | -0.5245 | 1.0620 | |
| MDA-MB-453 | TNBC | Luminal | MG-132 | Proteasome | Proteasome | 13.3 | uM | 14646.189 | 0.0776 | -0.8198 | 1.0620 | |
| MDA-MB-453 | TNBC | Luminal | MG-132 | Proteasome | Proteasome | 13.3 | uM | 14646.189 | 0.0776 | -0.8198 | 1.0620 | |
| MDA-MB-453 | TNBC | Luminal | MG-132 | Proteasome | Proteasome | 66.7 | uM | 14646.189 | 0.0979 | -0.7757 | 1.0620 | |
| MDA-MB-453 | TNBC | Luminal | MG-132 | Proteasome | Proteasome | 66.7 | uM | 14646.189 | 0.0979 | -0.7757 | 1.0620 | |
| MX1 | Unknown | Unknown | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 10644.145 | 1.0758 | 1.3704 | 0.4300 |