Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 21MT-1 | HER2amp | - | Methylglyoxal | 86.4 | uM | 13719.184 | 0.9555 | 0.8838 | 0.7600 | |||
| 21MT-1 | HER2amp | - | Methylglyoxal | 432 | uM | 13719.184 | 0.9380 | 0.8384 | 0.7600 | |||
| 21MT-1 | HER2amp | - | Methylglyoxal | 2160 | uM | 13719.184 | 0.2031 | -0.7545 | 0.7600 | |||
| 21MT-1 | HER2amp | - | Methylglyoxal | 10800 | uM | 13719.184 | 0.0731 | -0.9360 | 0.7600 | |||
| 21MT-1 | HER2amp | - | Methylglyoxal | 54000 | uM | 13719.184 | 0.0099 | -0.9954 | 0.7600 | |||
| 21NT | HER2amp | - | Methylglyoxal | 0.138 | uM | 13653.184 | 0.9611 | 0.9506 | 1.5871 | |||
| 21NT | HER2amp | - | Methylglyoxal | 0.691 | uM | 13653.184 | 0.9478 | 0.9335 | 1.5871 | |||
| 21NT | HER2amp | - | Methylglyoxal | 3.46 | uM | 13653.184 | 0.9538 | 0.9413 | 1.5871 | |||
| 21NT | HER2amp | - | Methylglyoxal | 17.3 | uM | 13653.184 | 0.9643 | 0.9548 | 1.5871 | |||
| 21NT | HER2amp | - | Methylglyoxal | 86.4 | uM | 13653.184 | 0.6453 | 0.5176 | 1.5871 | |||
| 21NT | HER2amp | - | Methylglyoxal | 432 | uM | 13653.184 | 0.8493 | 0.8044 | 1.5871 | |||
| 21NT | HER2amp | - | Methylglyoxal | 2160 | uM | 13653.184 | 0.2758 | -0.1118 | 1.5871 | |||
| 21NT | HER2amp | - | Methylglyoxal | 10800 | uM | 13653.184 | 0.0254 | -0.8023 | 1.5871 | |||
| 21NT | HER2amp | - | Methylglyoxal | 54000 | uM | 13653.184 | 0.0047 | -0.9322 | 1.5871 | |||
| 600MPE | HR+ | Luminal | Methylglyoxal | 0.138 | uM | 13091.184 | 0.9898 | 0.9745 | 0.8014 | |||
| 600MPE | HR+ | Luminal | Methylglyoxal | 0.691 | uM | 13091.184 | 0.9824 | 0.9562 | 0.8014 | |||
| 600MPE | HR+ | Luminal | Methylglyoxal | 3.46 | uM | 13091.184 | 0.9994 | 0.9984 | 0.8014 | |||
| 600MPE | HR+ | Luminal | Methylglyoxal | 17.3 | uM | 13091.184 | 0.9777 | 0.9445 | 0.8014 | |||
| 600MPE | HR+ | Luminal | Methylglyoxal | 86.4 | uM | 13091.184 | 0.9343 | 0.8373 | 0.8014 | |||
| 600MPE | HR+ | Luminal | Methylglyoxal | 432 | uM | 13091.184 | 0.8749 | 0.6928 | 0.8014 | |||
| 600MPE | HR+ | Luminal | Methylglyoxal | 2160 | uM | 13091.184 | 0.1411 | -0.8264 | 0.8014 | |||
| 600MPE | HR+ | Luminal | Methylglyoxal | 10800 | uM | 13091.184 | 0.0661 | -0.9325 | 0.8014 | |||
| 600MPE | HR+ | Luminal | Methylglyoxal | 54000 | uM | 13091.184 | 0.0005 | -0.9999 | 0.8014 | |||
| AU565 | HER2amp | Luminal | Methylglyoxal | 0.138 | uM | 13030.184 | 1.0865 | 1.3118 | 0.5725 | |||
| AU565 | HER2amp | Luminal | Methylglyoxal | 0.691 | uM | 13030.184 | 1.0459 | 1.1630 | 0.5725 |