Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM149PT | TNBC | Basal B | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 6.67 | uM | 10819.154 | 0.1602 | -0.1751 | 2.0680 | |
| SUM149PT | TNBC | Basal B | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 33.3 | uM | 10819.154 | 0.0016 | -0.9116 | 2.0680 | |
| SUM149PT | TNBC | Basal B | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.0000853 | uM | 11937.154 | 0.8906 | 0.9105 | 2.5304 | |
| SUM149PT | TNBC | Basal B | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.000427 | uM | 11937.154 | 0.8693 | 0.8923 | 2.5304 | |
| SUM149PT | TNBC | Basal B | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.00213 | uM | 11937.154 | 0.8582 | 0.8827 | 2.5304 | |
| SUM149PT | TNBC | Basal B | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.0107 | uM | 11937.154 | 0.7666 | 0.8006 | 2.5304 | |
| SUM149PT | TNBC | Basal B | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.0533 | uM | 11937.154 | 0.4928 | 0.5121 | 2.5304 | |
| SUM149PT | TNBC | Basal B | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.267 | uM | 11937.154 | 0.3771 | 0.3603 | 2.5304 | |
| SUM149PT | TNBC | Basal B | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 1.33 | uM | 11937.154 | 0.1593 | -0.0323 | 2.5304 | |
| SUM149PT | TNBC | Basal B | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 6.67 | uM | 11937.154 | 0.0979 | -0.2018 | 2.5304 | |
| SUM149PT | TNBC | Basal B | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 33.3 | uM | 11937.154 | 0.0073 | -0.7134 | 2.5304 | |
| SUM159PT | TNBC | Basal B | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.000256 | uM | 10520.142 | 1.1855 | 1.1101 | 3.1766 | |
| SUM159PT | TNBC | Basal B | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.00128 | uM | 10520.142 | 0.8049 | 0.8679 | 3.1766 | |
| SUM159PT | TNBC | Basal B | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.0064 | uM | 10520.142 | 1.1062 | 1.0646 | 3.1766 | |
| SUM159PT | TNBC | Basal B | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.032 | uM | 10520.142 | 0.9110 | 0.9422 | 3.1766 | |
| SUM159PT | TNBC | Basal B | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.16 | uM | 10520.142 | 0.6333 | 0.7322 | 3.1766 | |
| SUM159PT | TNBC | Basal B | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.8 | uM | 10520.142 | 0.2991 | 0.3678 | 3.1766 | |
| SUM159PT | TNBC | Basal B | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 4 | uM | 10520.142 | 0.1072 | -0.0098 | 3.1766 | |
| SUM159PT | TNBC | Basal B | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 20 | uM | 10520.142 | 0.0475 | -0.2337 | 3.1766 | |
| SUM159PT | TNBC | Basal B | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 100 | uM | 10520.142 | 0.0012 | -0.7591 | 3.1766 | |
| SUM159PT | TNBC | Basal B | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.0000853 | uM | 11057.154 | 1.0548 | 1.0279 | 3.8498 | |
| SUM159PT | TNBC | Basal B | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.000427 | uM | 11057.154 | 0.9496 | 0.9733 | 3.8498 | |
| SUM159PT | TNBC | Basal B | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.00213 | uM | 11057.154 | 0.9867 | 0.9930 | 3.8498 | |
| SUM159PT | TNBC | Basal B | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.0107 | uM | 11057.154 | 0.9214 | 0.9579 | 3.8498 | |
| SUM159PT | TNBC | Basal B | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.0533 | uM | 11057.154 | 0.7484 | 0.8550 | 3.8498 |