Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC38 | TNBC | Basal B | IKK16 | IKK | NFKB | 0.533 | uM | 7468.093 | 0.8948 | 0.8473 | 1.4007 | |
| HCC38 | TNBC | Basal B | IKK16 | IKK | NFKB | 2.67 | uM | 7468.093 | 0.8039 | 0.7113 | 1.4007 | |
| HCC38 | TNBC | Basal B | IKK16 | IKK | NFKB | 13.3 | uM | 7468.093 | 0.0025 | -0.9724 | 1.4007 | |
| HCC38 | TNBC | Basal B | IKK16 | IKK | NFKB | 66.7 | uM | 7468.093 | 0.0027 | -0.9707 | 1.4007 | |
| HCC38 | TNBC | Basal B | IKK16 | IKK | NFKB | 0.000171 | uM | 10418.093 | 1.1125 | 1.2281 | 0.9872 | |
| HCC38 | TNBC | Basal B | IKK16 | IKK | NFKB | 0.000853 | uM | 10418.093 | 1.0362 | 1.0734 | 0.9872 | |
| HCC38 | TNBC | Basal B | IKK16 | IKK | NFKB | 0.00427 | uM | 10418.093 | 1.0162 | 1.0327 | 0.9872 | |
| HCC38 | TNBC | Basal B | IKK16 | IKK | NFKB | 0.0213 | uM | 10418.093 | 1.0103 | 1.0208 | 0.9872 | |
| HCC38 | TNBC | Basal B | IKK16 | IKK | NFKB | 0.107 | uM | 10418.093 | 1.0118 | 1.0239 | 0.9872 | |
| HCC38 | TNBC | Basal B | IKK16 | IKK | NFKB | 0.533 | uM | 10418.093 | 0.9644 | 0.9278 | 0.9872 | |
| HCC38 | TNBC | Basal B | IKK16 | IKK | NFKB | 2.67 | uM | 10418.093 | 0.7961 | 0.5876 | 0.9872 | |
| HCC38 | TNBC | Basal B | IKK16 | IKK | NFKB | 13.3 | uM | 10418.093 | 0.0017 | -0.9969 | 0.9872 | |
| HCC38 | TNBC | Basal B | IKK16 | IKK | NFKB | 66.7 | uM | 10418.093 | 0.0027 | -0.9950 | 0.9872 | |
| HCC38 | TNBC | Basal B | IKK16 | IKK | NFKB | 0.000171 | uM | 10578.1 | 0.9998 | 0.9998 | 1.6202 | |
| HCC38 | TNBC | Basal B | IKK16 | IKK | NFKB | 0.000853 | uM | 10578.1 | 0.9376 | 0.9220 | 1.6202 | |
| HCC38 | TNBC | Basal B | IKK16 | IKK | NFKB | 0.00427 | uM | 10578.1 | 0.9845 | 0.9808 | 1.6202 | |
| HCC38 | TNBC | Basal B | IKK16 | IKK | NFKB | 0.0213 | uM | 10578.1 | 0.9991 | 0.9989 | 1.6202 | |
| HCC38 | TNBC | Basal B | IKK16 | IKK | NFKB | 0.107 | uM | 10578.1 | 0.9890 | 0.9864 | 1.6202 | |
| HCC38 | TNBC | Basal B | IKK16 | IKK | NFKB | 0.533 | uM | 10578.1 | 0.9405 | 0.9256 | 1.6202 | |
| HCC38 | TNBC | Basal B | IKK16 | IKK | NFKB | 2.67 | uM | 10578.1 | 0.8582 | 0.8199 | 1.6202 | |
| HCC38 | TNBC | Basal B | IKK16 | IKK | NFKB | 13.3 | uM | 10578.1 | 0.0028 | -0.9474 | 1.6202 | |
| HCC38 | TNBC | Basal B | IKK16 | IKK | NFKB | 66.7 | uM | 10578.1 | 0.0024 | -0.9511 | 1.6202 | |
| HCC70 | TNBC | Basal A | IKK16 | IKK | NFKB | 0.000171 | uM | 7470.093 | 1.0050 | 1.0093 | 1.0798 | |
| HCC70 | TNBC | Basal A | IKK16 | IKK | NFKB | 0.000853 | uM | 7470.093 | 0.9570 | 0.9202 | 1.0798 | |
| HCC70 | TNBC | Basal A | IKK16 | IKK | NFKB | 0.00427 | uM | 7470.093 | 0.9725 | 0.9490 | 1.0798 |