Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM149PT | TNBC | Basal B | Ibandronate | FDPS | 12 | uM | 10819.143 | 0.9276 | 0.9345 | 2.2570 | ||
| SUM149PT | TNBC | Basal B | Ibandronate | FDPS | 60 | uM | 10819.143 | 0.7352 | 0.7452 | 2.2570 | ||
| SUM149PT | TNBC | Basal B | Ibandronate | FDPS | 300 | uM | 10819.143 | 0.4993 | 0.4702 | 2.2570 | ||
| SUM149PT | TNBC | Basal B | Ibandronate | FDPS | 1500 | uM | 10819.143 | 0.2383 | 0.0594 | 2.2570 | ||
| SUM149PT | TNBC | Basal B | Ibandronate | FDPS | 0.00384 | uM | 11937.143 | 0.9807 | 0.9832 | 2.3169 | ||
| SUM149PT | TNBC | Basal B | Ibandronate | FDPS | 0.0192 | uM | 11937.143 | 0.9833 | 0.9856 | 2.3169 | ||
| SUM149PT | TNBC | Basal B | Ibandronate | FDPS | 0.096 | uM | 11937.143 | 0.9677 | 0.9718 | 2.3169 | ||
| SUM149PT | TNBC | Basal B | Ibandronate | FDPS | 0.48 | uM | 11937.143 | 1.0014 | 1.0012 | 2.3169 | ||
| SUM149PT | TNBC | Basal B | Ibandronate | FDPS | 2.4 | uM | 11937.143 | 0.9362 | 0.9439 | 2.3169 | ||
| SUM149PT | TNBC | Basal B | Ibandronate | FDPS | 12 | uM | 11937.143 | 0.9155 | 0.9252 | 2.3169 | ||
| SUM149PT | TNBC | Basal B | Ibandronate | FDPS | 60 | uM | 11937.143 | 0.6867 | 0.7005 | 2.3169 | ||
| SUM149PT | TNBC | Basal B | Ibandronate | FDPS | 300 | uM | 11937.143 | 0.5481 | 0.5429 | 2.3169 | ||
| SUM149PT | TNBC | Basal B | Ibandronate | FDPS | 1500 | uM | 11937.143 | 0.2101 | 0.0199 | 2.3169 | ||
| SUM159PT | TNBC | Basal B | Ibandronate | FDPS | 0.00384 | uM | 11057.143 | 0.9487 | 0.9747 | 4.1426 | ||
| SUM159PT | TNBC | Basal B | Ibandronate | FDPS | 0.0192 | uM | 11057.143 | 0.9855 | 0.9930 | 4.1426 | ||
| SUM159PT | TNBC | Basal B | Ibandronate | FDPS | 0.096 | uM | 11057.143 | 1.0496 | 1.0235 | 4.1426 | ||
| SUM159PT | TNBC | Basal B | Ibandronate | FDPS | 0.48 | uM | 11057.143 | 1.1333 | 1.0613 | 4.1426 | ||
| SUM159PT | TNBC | Basal B | Ibandronate | FDPS | 2.4 | uM | 11057.143 | 0.9258 | 0.9631 | 4.1426 | ||
| SUM159PT | TNBC | Basal B | Ibandronate | FDPS | 12 | uM | 11057.143 | 0.9069 | 0.9534 | 4.1426 | ||
| SUM159PT | TNBC | Basal B | Ibandronate | FDPS | 60 | uM | 11057.143 | 0.3800 | 0.5834 | 4.1426 | ||
| SUM159PT | TNBC | Basal B | Ibandronate | FDPS | 300 | uM | 11057.143 | 0.2205 | 0.3885 | 4.1426 | ||
| SUM159PT | TNBC | Basal B | Ibandronate | FDPS | 1500 | uM | 11057.143 | 0.1397 | 0.2436 | 4.1426 | ||
| SUM185PE | TNBC | Luminal | Ibandronate | FDPS | 0.00384 | uM | 12269.143 | 1.4815 | 6.1435 | 0.3088 | ||
| SUM185PE | TNBC | Luminal | Ibandronate | FDPS | 0.0192 | uM | 12269.143 | 1.3938 | 4.8625 | 0.3088 | ||
| SUM185PE | TNBC | Luminal | Ibandronate | FDPS | 0.096 | uM | 12269.143 | 1.0645 | 1.4486 | 0.3088 |