Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UACC-812 | HER2amp | Luminal | GSK923295 | CENPE | Kinesin | 0.0533 | uM | 7926.001 | 0.6860 | 0.2377 | 0.7852 | |
| UACC-812 | HER2amp | Luminal | GSK923295 | CENPE | Kinesin | 0.267 | uM | 7926.001 | 0.6588 | 0.1755 | 0.7852 | |
| UACC-812 | HER2amp | Luminal | GSK923295 | CENPE | Kinesin | 1.33 | uM | 7926.001 | 0.6650 | 0.1895 | 0.7852 | |
| UACC-812 | HER2amp | Luminal | GSK923295 | CENPE | Kinesin | 6.67 | uM | 7926.001 | 0.6895 | 0.2456 | 0.7852 | |
| UACC-812 | HER2amp | Luminal | GSK923295 | CENPE | Kinesin | 33.3 | uM | 7926.001 | 0.7074 | 0.2868 | 0.7852 | |
| UACC-812 | HER2amp | Luminal | GSK923295 | CENPE | Kinesin | 0.0000853 | uM | 9913.001 | 1.1543 | 2.2028 | 0.3047 | |
| UACC-812 | HER2amp | Luminal | GSK923295 | CENPE | Kinesin | 0.000427 | uM | 9913.001 | 0.9083 | 0.4587 | 0.3047 | |
| UACC-812 | HER2amp | Luminal | GSK923295 | CENPE | Kinesin | 0.00213 | uM | 9913.001 | 1.1702 | 2.3501 | 0.3047 | |
| UACC-812 | HER2amp | Luminal | GSK923295 | CENPE | Kinesin | 0.0107 | uM | 9913.001 | 0.9017 | 0.4239 | 0.3047 | |
| UACC-812 | HER2amp | Luminal | GSK923295 | CENPE | Kinesin | 0.0533 | uM | 9913.001 | 0.6981 | -0.3852 | 0.3047 | |
| UACC-812 | HER2amp | Luminal | GSK923295 | CENPE | Kinesin | 0.267 | uM | 9913.001 | 0.6137 | -0.5971 | 0.3047 | |
| UACC-812 | HER2amp | Luminal | GSK923295 | CENPE | Kinesin | 1.33 | uM | 9913.001 | 0.6652 | -0.4752 | 0.3047 | |
| UACC-812 | HER2amp | Luminal | GSK923295 | CENPE | Kinesin | 6.67 | uM | 9913.001 | 0.7535 | -0.2099 | 0.3047 | |
| UACC-812 | HER2amp | Luminal | GSK923295 | CENPE | Kinesin | 33.3 | uM | 9913.001 | 0.7093 | -0.3520 | 0.3047 | |
| UACC-812 | HER2amp | Luminal | GSK923295 | CENPE | Kinesin | 0.0000853 | uM | 10150.001 | 1.0132 | 1.0819 | 0.3255 | |
| UACC-812 | HER2amp | Luminal | GSK923295 | CENPE | Kinesin | 0.000427 | uM | 10150.001 | 1.0469 | 1.3026 | 0.3255 | |
| UACC-812 | HER2amp | Luminal | GSK923295 | CENPE | Kinesin | 0.00213 | uM | 10150.001 | 1.0839 | 1.5616 | 0.3255 | |
| UACC-812 | HER2amp | Luminal | GSK923295 | CENPE | Kinesin | 0.0107 | uM | 10150.001 | 0.8835 | 0.3668 | 0.3255 | |
| UACC-812 | HER2amp | Luminal | GSK923295 | CENPE | Kinesin | 0.0533 | uM | 10150.001 | 0.5607 | -0.6619 | 0.3255 | |
| UACC-812 | HER2amp | Luminal | GSK923295 | CENPE | Kinesin | 0.267 | uM | 10150.001 | 0.5055 | -0.7540 | 0.3255 | |
| UACC-812 | HER2amp | Luminal | GSK923295 | CENPE | Kinesin | 1.33 | uM | 10150.001 | 0.6012 | -0.5811 | 0.3255 | |
| UACC-812 | HER2amp | Luminal | GSK923295 | CENPE | Kinesin | 6.67 | uM | 10150.001 | 0.6130 | -0.5554 | 0.3255 | |
| UACC-812 | HER2amp | Luminal | GSK923295 | CENPE | Kinesin | 33.3 | uM | 10150.001 | 0.6005 | -0.5826 | 0.3255 | |
| UACC-812 | HER2amp | Luminal | GSK923295 | CENPE | Kinesin | 0.0000853 | uM | 10151.001 | 1.0594 | 1.2937 | 0.4212 | |
| UACC-812 | HER2amp | Luminal | GSK923295 | CENPE | Kinesin | 0.000427 | uM | 10151.001 | 0.9321 | 0.6924 | 0.4212 |