Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM159PT | TNBC | Basal B | GSK923295 | CENPE | Kinesin | 0.000427 | uM | 7918.001 | 1.0241 | 1.0166 | 2.8818 | |
| SUM159PT | TNBC | Basal B | GSK923295 | CENPE | Kinesin | 0.00213 | uM | 7918.001 | 1.2123 | 1.1382 | 2.8818 | |
| SUM159PT | TNBC | Basal B | GSK923295 | CENPE | Kinesin | 0.0107 | uM | 7918.001 | 1.0664 | 1.0452 | 2.8818 | |
| SUM159PT | TNBC | Basal B | GSK923295 | CENPE | Kinesin | 0.0533 | uM | 7918.001 | 0.2857 | 0.2949 | 2.8818 | |
| SUM159PT | TNBC | Basal B | GSK923295 | CENPE | Kinesin | 0.267 | uM | 7918.001 | 0.3497 | 0.3889 | 2.8818 | |
| SUM159PT | TNBC | Basal B | GSK923295 | CENPE | Kinesin | 1.33 | uM | 7918.001 | 0.1771 | 0.0968 | 2.8818 | |
| SUM159PT | TNBC | Basal B | GSK923295 | CENPE | Kinesin | 6.67 | uM | 7918.001 | 0.2472 | 0.2315 | 2.8818 | |
| SUM159PT | TNBC | Basal B | GSK923295 | CENPE | Kinesin | 33.3 | uM | 7918.001 | 0.0144 | -0.5406 | 2.8818 | |
| SUM159PT | TNBC | Basal B | GSK923295 | CENPE | Kinesin | 0.0000853 | uM | 7920.001 | 1.0959 | 1.0420 | 4.4085 | |
| SUM159PT | TNBC | Basal B | GSK923295 | CENPE | Kinesin | 0.000427 | uM | 7920.001 | 1.0419 | 1.0187 | 4.4085 | |
| SUM159PT | TNBC | Basal B | GSK923295 | CENPE | Kinesin | 0.00213 | uM | 7920.001 | 1.0962 | 1.0421 | 4.4085 | |
| SUM159PT | TNBC | Basal B | GSK923295 | CENPE | Kinesin | 0.0107 | uM | 7920.001 | 0.9619 | 0.9825 | 4.4085 | |
| SUM159PT | TNBC | Basal B | GSK923295 | CENPE | Kinesin | 0.0533 | uM | 7920.001 | 0.2170 | 0.4142 | 4.4085 | |
| SUM159PT | TNBC | Basal B | GSK923295 | CENPE | Kinesin | 0.267 | uM | 7920.001 | 0.1187 | 0.2333 | 4.4085 | |
| SUM159PT | TNBC | Basal B | GSK923295 | CENPE | Kinesin | 1.33 | uM | 7920.001 | 0.1195 | 0.2353 | 4.4085 | |
| SUM159PT | TNBC | Basal B | GSK923295 | CENPE | Kinesin | 6.67 | uM | 7920.001 | 0.1598 | 0.3193 | 4.4085 | |
| SUM159PT | TNBC | Basal B | GSK923295 | CENPE | Kinesin | 33.3 | uM | 7920.001 | 0.0530 | 0.0271 | 4.4085 | |
| SUM159PT | TNBC | Basal B | GSK923295 | CENPE | Kinesin | 0.0000853 | uM | 9844.001 | 1.1017 | 1.0838 | 2.3587 | |
| SUM159PT | TNBC | Basal B | GSK923295 | CENPE | Kinesin | 0.000427 | uM | 9844.001 | 1.0093 | 1.0078 | 2.3587 | |
| SUM159PT | TNBC | Basal B | GSK923295 | CENPE | Kinesin | 0.00213 | uM | 9844.001 | 1.1390 | 1.1135 | 2.3587 | |
| SUM159PT | TNBC | Basal B | GSK923295 | CENPE | Kinesin | 0.0107 | uM | 9844.001 | 0.9807 | 0.9836 | 2.3587 | |
| SUM159PT | TNBC | Basal B | GSK923295 | CENPE | Kinesin | 0.0533 | uM | 9844.001 | 0.5362 | 0.5356 | 2.3587 | |
| SUM159PT | TNBC | Basal B | GSK923295 | CENPE | Kinesin | 0.267 | uM | 9844.001 | 0.1991 | 0.0088 | 2.3587 | |
| SUM159PT | TNBC | Basal B | GSK923295 | CENPE | Kinesin | 1.33 | uM | 9844.001 | 0.2239 | 0.0604 | 2.3587 | |
| SUM159PT | TNBC | Basal B | GSK923295 | CENPE | Kinesin | 6.67 | uM | 9844.001 | 0.2739 | 0.1551 | 2.3587 |