Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)

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Cell Clinical Subtype Transcriptional Subtype Small Molecule Antibody Perturbagen Target Perturbagen Class Perturbagen Concentration Perturbagen Conc Unit Biological Replicate ID Relative Cell Count Normalized Growth Rate Inhibition Value Nominal Division Rate
MDA-MB-175-VII
HR+
Luminal
 GSK461364
PLK1
PLK
0.0000853
uM
7885.001
 1.0345 1.1113 0.6265
MDA-MB-175-VII
HR+
Luminal
 GSK461364
PLK1
PLK
0.000427
uM
7885.001
 1.1275 1.4223 0.6265
MDA-MB-175-VII
HR+
Luminal
 GSK461364
PLK1
PLK
0.00213
uM
7885.001
 1.0127 1.0406 0.6265
MDA-MB-175-VII
HR+
Luminal
 GSK461364
PLK1
PLK
0.0107
uM
7885.001
 0.9998 0.9993 0.6265
MDA-MB-175-VII
HR+
Luminal
 GSK461364
PLK1
PLK
0.0533
uM
7885.001
 0.8071 0.4206 0.6265
MDA-MB-175-VII
HR+
Luminal
 GSK461364
PLK1
PLK
0.267
uM
7885.001
 0.8796 0.6297 0.6265
MDA-MB-175-VII
HR+
Luminal
 GSK461364
PLK1
PLK
1.33
uM
7885.001
 0.9921 0.9749 0.6265
MDA-MB-175-VII
HR+
Luminal
 GSK461364
PLK1
PLK
6.67
uM
7885.001
 0.8977 0.6834 0.6265
MDA-MB-175-VII
HR+
Luminal
 GSK461364
PLK1
PLK
33.3
uM
7885.001
 0.3328 -0.6546 0.6265
MDA-MB-175-VII
HR+
Luminal
 GSK461364
PLK1
PLK
0.0000853
uM
7886.001
 0.9998 0.9996 0.7999
MDA-MB-175-VII
HR+
Luminal
 GSK461364
PLK1
PLK
0.000427
uM
7886.001
 1.0774 1.1954 0.7999
MDA-MB-175-VII
HR+
Luminal
 GSK461364
PLK1
PLK
0.00213
uM
7886.001
 0.7837 0.4748 0.7999
MDA-MB-175-VII
HR+
Luminal
 GSK461364
PLK1
PLK
0.0107
uM
7886.001
 0.7321 0.3544 0.7999
MDA-MB-175-VII
HR+
Luminal
 GSK461364
PLK1
PLK
0.0533
uM
7886.001
 0.7287 0.3465 0.7999
MDA-MB-175-VII
HR+
Luminal
 GSK461364
PLK1
PLK
0.267
uM
7886.001
 0.8809 0.7067 0.7999
MDA-MB-175-VII
HR+
Luminal
 GSK461364
PLK1
PLK
1.33
uM
7886.001
 0.9378 0.8457 0.7999
MDA-MB-175-VII
HR+
Luminal
 GSK461364
PLK1
PLK
6.67
uM
7886.001
 0.7280 0.3448 0.7999
MDA-MB-175-VII
HR+
Luminal
 GSK461364
PLK1
PLK
33.3
uM
7886.001
 0.0229 -0.9822 0.7999
MDA-MB-231
TNBC
Basal B
 GSK461364
PLK1
PLK
0.0000853
uM
7892.001
 1.0188 1.0142 2.6314
MDA-MB-231
TNBC
Basal B
 GSK461364
PLK1
PLK
0.000427
uM
7892.001
 1.0209 1.0158 2.6314
MDA-MB-231
TNBC
Basal B
 GSK461364
PLK1
PLK
0.00213
uM
7892.001
 0.9803 0.9849 2.6314
MDA-MB-231
TNBC
Basal B
 GSK461364
PLK1
PLK
0.0107
uM
7892.001
 0.8606 0.8891 2.6314
MDA-MB-231
TNBC
Basal B
 GSK461364
PLK1
PLK
0.0533
uM
7892.001
 0.3447 0.3342 2.6314
MDA-MB-231
TNBC
Basal B
 GSK461364
PLK1
PLK
0.267
uM
7892.001
 0.3962 0.4068 2.6314
MDA-MB-231
TNBC
Basal B
 GSK461364
PLK1
PLK
1.33
uM
7892.001
 0.4734 0.5052 2.6314