Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM52PE | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.000171 | uM | 7541.098 | 0.8701 | 0.8361 | 1.6271 | |
| SUM52PE | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.000853 | uM | 7541.098 | 0.8911 | 0.8631 | 1.6271 | |
| SUM52PE | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.00427 | uM | 7541.098 | 0.9355 | 0.9197 | 1.6271 | |
| SUM52PE | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.0213 | uM | 7541.098 | 0.8988 | 0.8731 | 1.6271 | |
| SUM52PE | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.107 | uM | 7541.098 | 0.8534 | 0.8143 | 1.6271 | |
| SUM52PE | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.533 | uM | 7541.098 | 0.8111 | 0.7585 | 1.6271 | |
| SUM52PE | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 2.67 | uM | 7541.098 | 0.5814 | 0.4330 | 1.6271 | |
| SUM52PE | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 13.3 | uM | 7541.098 | 0.0945 | -0.5308 | 1.6271 | |
| SUM52PE | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 66.7 | uM | 7541.098 | 0.0431 | -0.7103 | 1.6271 | |
| T47D | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.000171 | uM | 7542.092 | 0.9792 | 0.9729 | 1.5380 | |
| T47D | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.000853 | uM | 7542.092 | 0.9547 | 0.9406 | 1.5380 | |
| T47D | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.00427 | uM | 7542.092 | 1.0616 | 1.0792 | 1.5380 | |
| T47D | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.0213 | uM | 7542.092 | 0.9947 | 0.9932 | 1.5380 | |
| T47D | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.107 | uM | 7542.092 | 0.9488 | 0.9328 | 1.5380 | |
| T47D | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.533 | uM | 7542.092 | 0.9173 | 0.8909 | 1.5380 | |
| T47D | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 2.67 | uM | 7542.092 | 0.8340 | 0.7773 | 1.5380 | |
| T47D | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 13.3 | uM | 7542.092 | 0.6820 | 0.5594 | 1.5380 | |
| T47D | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 66.7 | uM | 7542.092 | 0.0194 | -0.8457 | 1.5380 | |
| T47D | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.000171 | uM | 7542.098 | 1.0397 | 1.0606 | 1.3028 | |
| T47D | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.000853 | uM | 7542.098 | 0.9602 | 0.9386 | 1.3028 | |
| T47D | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.00427 | uM | 7542.098 | 0.9930 | 0.9893 | 1.3028 | |
| T47D | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.0213 | uM | 7542.098 | 0.9300 | 0.8916 | 1.3028 | |
| T47D | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.107 | uM | 7542.098 | 0.9953 | 0.9927 | 1.3028 | |
| T47D | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.533 | uM | 7542.098 | 0.9277 | 0.8881 | 1.3028 | |
| T47D | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 2.67 | uM | 7542.098 | 0.8882 | 0.8261 | 1.3028 |