Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1395 | TNBC | Basal B | 5-FU | TYMS | TYMS | 6.15 | uM | 7816.017 | 1.0047 | 1.0076 | 1.2318 | |
| HCC1395 | TNBC | Basal B | 5-FU | TYMS | TYMS | 30.7 | uM | 7816.017 | 0.9154 | 0.8614 | 1.2318 | |
| HCC1395 | TNBC | Basal B | 5-FU | TYMS | TYMS | 154 | uM | 7816.017 | 0.8857 | 0.8123 | 1.2318 | |
| HCC1395 | TNBC | Basal B | 5-FU | TYMS | TYMS | 769 | uM | 7816.017 | 0.8122 | 0.6893 | 1.2318 | |
| HCC1395 | TNBC | Basal B | 5-FU | TYMS | TYMS | 3840 | uM | 7816.017 | 0.7356 | 0.5587 | 1.2318 | |
| HCC1395 | TNBC | Basal B | 5-FU | TYMS | TYMS | 19200 | uM | 7816.017 | 0.6417 | 0.3951 | 1.2318 | |
| HCC1395 | TNBC | Basal B | 5-FU | TYMS | TYMS | 0.0492 | uM | 9258.03 | 1.2452 | 2.4532 | 0.4015 | |
| HCC1395 | TNBC | Basal B | 5-FU | TYMS | TYMS | 0.246 | uM | 9258.03 | 1.1669 | 1.9372 | 0.4015 | |
| HCC1395 | TNBC | Basal B | 5-FU | TYMS | TYMS | 1.23 | uM | 9258.03 | 1.1185 | 1.6433 | 0.4015 | |
| HCC1395 | TNBC | Basal B | 5-FU | TYMS | TYMS | 6.15 | uM | 9258.03 | 1.1030 | 1.5532 | 0.4015 | |
| HCC1395 | TNBC | Basal B | 5-FU | TYMS | TYMS | 30.7 | uM | 9258.03 | 1.0331 | 1.1689 | 0.4015 | |
| HCC1395 | TNBC | Basal B | 5-FU | TYMS | TYMS | 154 | uM | 9258.03 | 1.0276 | 1.1404 | 0.4015 | |
| HCC1395 | TNBC | Basal B | 5-FU | TYMS | TYMS | 769 | uM | 9258.03 | 0.8678 | 0.4050 | 0.4015 | |
| HCC1395 | TNBC | Basal B | 5-FU | TYMS | TYMS | 3840 | uM | 9258.03 | 0.5995 | -0.4407 | 0.4015 | |
| HCC1395 | TNBC | Basal B | 5-FU | TYMS | TYMS | 19200 | uM | 9258.03 | 0.3465 | -0.8573 | 0.4015 | |
| HCC1419 | HER2amp | Luminal | 5-FU | TYMS | TYMS | 0.0492 | uM | 7820.017 | 0.9733 | 0.9233 | 0.6915 | |
| HCC1419 | HER2amp | Luminal | 5-FU | TYMS | TYMS | 0.246 | uM | 7820.017 | 0.9566 | 0.8758 | 0.6915 | |
| HCC1419 | HER2amp | Luminal | 5-FU | TYMS | TYMS | 1.23 | uM | 7820.017 | 1.0217 | 1.0631 | 0.6915 | |
| HCC1419 | HER2amp | Luminal | 5-FU | TYMS | TYMS | 6.15 | uM | 7820.017 | 0.9673 | 0.9061 | 0.6915 | |
| HCC1419 | HER2amp | Luminal | 5-FU | TYMS | TYMS | 30.7 | uM | 7820.017 | 0.8808 | 0.6647 | 0.6915 | |
| HCC1419 | HER2amp | Luminal | 5-FU | TYMS | TYMS | 154 | uM | 7820.017 | 0.8449 | 0.5674 | 0.6915 | |
| HCC1419 | HER2amp | Luminal | 5-FU | TYMS | TYMS | 769 | uM | 7820.017 | 0.5789 | -0.0928 | 0.6915 | |
| HCC1419 | HER2amp | Luminal | 5-FU | TYMS | TYMS | 3840 | uM | 7820.017 | 0.3733 | -0.5189 | 0.6915 | |
| HCC1419 | HER2amp | Luminal | 5-FU | TYMS | TYMS | 19200 | uM | 7820.017 | 0.2297 | -0.7617 | 0.6915 | |
| HCC1419 | HER2amp | Luminal | 5-FU | TYMS | TYMS | 0.0492 | uM | 7821.017 | 1.0343 | 1.1863 | 0.3792 |