Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BT-549 | TNBC | Basal B | 5-FU | TYMS | TYMS | 1.23 | uM | 7804.017 | 0.9902 | 0.9925 | 2.5963 | |
| BT-549 | TNBC | Basal B | 5-FU | TYMS | TYMS | 6.15 | uM | 7804.017 | 0.9669 | 0.9742 | 2.5963 | |
| BT-549 | TNBC | Basal B | 5-FU | TYMS | TYMS | 30.7 | uM | 7804.017 | 0.7997 | 0.8350 | 2.5963 | |
| BT-549 | TNBC | Basal B | 5-FU | TYMS | TYMS | 154 | uM | 7804.017 | 0.6232 | 0.6670 | 2.5963 | |
| BT-549 | TNBC | Basal B | 5-FU | TYMS | TYMS | 769 | uM | 7804.017 | 0.4563 | 0.4784 | 2.5963 | |
| BT-549 | TNBC | Basal B | 5-FU | TYMS | TYMS | 3840 | uM | 7804.017 | 0.3003 | 0.2584 | 2.5963 | |
| BT-549 | TNBC | Basal B | 5-FU | TYMS | TYMS | 19200 | uM | 7804.017 | 0.1931 | 0.0616 | 2.5963 | |
| BT-549 | TNBC | Basal B | 5-FU | TYMS | TYMS | 0.0492 | uM | 10261.131 | 1.0440 | 1.0362 | 2.3992 | |
| BT-549 | TNBC | Basal B | 5-FU | TYMS | TYMS | 0.246 | uM | 10261.131 | 1.0095 | 1.0079 | 2.3992 | |
| BT-549 | TNBC | Basal B | 5-FU | TYMS | TYMS | 1.23 | uM | 10261.131 | 0.9844 | 0.9869 | 2.3992 | |
| BT-549 | TNBC | Basal B | 5-FU | TYMS | TYMS | 6.15 | uM | 10261.131 | 0.8855 | 0.9011 | 2.3992 | |
| BT-549 | TNBC | Basal B | 5-FU | TYMS | TYMS | 30.7 | uM | 10261.131 | 0.6896 | 0.7130 | 2.3992 | |
| BT-549 | TNBC | Basal B | 5-FU | TYMS | TYMS | 154 | uM | 10261.131 | 0.4962 | 0.4934 | 2.3992 | |
| BT-549 | TNBC | Basal B | 5-FU | TYMS | TYMS | 769 | uM | 10261.131 | 0.3979 | 0.3620 | 2.3992 | |
| BT-549 | TNBC | Basal B | 5-FU | TYMS | TYMS | 3840 | uM | 10261.131 | 0.2801 | 0.1766 | 2.3992 | |
| BT-549 | TNBC | Basal B | 5-FU | TYMS | TYMS | 19200 | uM | 10261.131 | 0.1834 | -0.0136 | 2.3992 | |
| CAMA-1 | HR+ | Luminal | 5-FU | TYMS | TYMS | 0.0492 | uM | 9210.131 | 1.0132 | 1.0294 | 0.9004 | |
| CAMA-1 | HR+ | Luminal | 5-FU | TYMS | TYMS | 0.246 | uM | 9210.131 | 0.8896 | 0.7563 | 0.9004 | |
| CAMA-1 | HR+ | Luminal | 5-FU | TYMS | TYMS | 1.23 | uM | 9210.131 | 0.9949 | 0.9886 | 0.9004 | |
| CAMA-1 | HR+ | Luminal | 5-FU | TYMS | TYMS | 6.15 | uM | 9210.131 | 0.9318 | 0.8491 | 0.9004 | |
| CAMA-1 | HR+ | Luminal | 5-FU | TYMS | TYMS | 30.7 | uM | 9210.131 | 0.9000 | 0.7792 | 0.9004 | |
| CAMA-1 | HR+ | Luminal | 5-FU | TYMS | TYMS | 154 | uM | 9210.131 | 0.7805 | 0.5188 | 0.9004 | |
| CAMA-1 | HR+ | Luminal | 5-FU | TYMS | TYMS | 769 | uM | 9210.131 | 0.7150 | 0.3780 | 0.9004 | |
| CAMA-1 | HR+ | Luminal | 5-FU | TYMS | TYMS | 3840 | uM | 9210.131 | 0.3428 | -0.3909 | 0.9004 | |
| CAMA-1 | HR+ | Luminal | 5-FU | TYMS | TYMS | 19200 | uM | 9210.131 | 0.3007 | -0.4736 | 0.9004 |