Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC38 | TNBC | Basal B | GSK1070916 | AURK | AURK | 0.00213 | uM | 9469.001 | 1.0283 | 1.0554 | 1.0202 | |
| HCC38 | TNBC | Basal B | GSK1070916 | AURK | AURK | 0.0107 | uM | 9469.001 | 0.9776 | 0.9561 | 1.0202 | |
| HCC38 | TNBC | Basal B | GSK1070916 | AURK | AURK | 0.0533 | uM | 9469.001 | 0.7547 | 0.5179 | 1.0202 | |
| HCC38 | TNBC | Basal B | GSK1070916 | AURK | AURK | 0.267 | uM | 9469.001 | 0.7413 | 0.4914 | 1.0202 | |
| HCC38 | TNBC | Basal B | GSK1070916 | AURK | AURK | 1.33 | uM | 9469.001 | 0.7521 | 0.5126 | 1.0202 | |
| HCC38 | TNBC | Basal B | GSK1070916 | AURK | AURK | 6.67 | uM | 9469.001 | 0.4092 | -0.1670 | 1.0202 | |
| HCC38 | TNBC | Basal B | GSK1070916 | AURK | AURK | 33.3 | uM | 9469.001 | 0.0105 | -0.9770 | 1.0202 | |
| HCC70 | TNBC | Basal A | GSK1070916 | AURK | AURK | 0.0000853 | uM | 7856.001 | 1.1516 | 1.4393 | 0.7111 | |
| HCC70 | TNBC | Basal A | GSK1070916 | AURK | AURK | 0.000427 | uM | 7856.001 | 1.0499 | 1.1417 | 0.7111 | |
| HCC70 | TNBC | Basal A | GSK1070916 | AURK | AURK | 0.00213 | uM | 7856.001 | 1.1076 | 1.3091 | 0.7111 | |
| HCC70 | TNBC | Basal A | GSK1070916 | AURK | AURK | 0.0107 | uM | 7856.001 | 1.0025 | 1.0072 | 0.7111 | |
| HCC70 | TNBC | Basal A | GSK1070916 | AURK | AURK | 0.0533 | uM | 7856.001 | 0.7467 | 0.3262 | 0.7111 | |
| HCC70 | TNBC | Basal A | GSK1070916 | AURK | AURK | 0.267 | uM | 7856.001 | 0.7361 | 0.2999 | 0.7111 | |
| HCC70 | TNBC | Basal A | GSK1070916 | AURK | AURK | 1.33 | uM | 7856.001 | 0.7621 | 0.3649 | 0.7111 | |
| HCC70 | TNBC | Basal A | GSK1070916 | AURK | AURK | 6.67 | uM | 7856.001 | 0.6038 | -0.0162 | 0.7111 | |
| HCC70 | TNBC | Basal A | GSK1070916 | AURK | AURK | 33.3 | uM | 7856.001 | 0.3234 | -0.5911 | 0.7111 | |
| HCC70 | TNBC | Basal A | GSK1070916 | AURK | AURK | 0.0000853 | uM | 7857.001 | 0.9938 | 0.9894 | 1.1724 | |
| HCC70 | TNBC | Basal A | GSK1070916 | AURK | AURK | 0.000427 | uM | 7857.001 | 0.9818 | 0.9688 | 1.1724 | |
| HCC70 | TNBC | Basal A | GSK1070916 | AURK | AURK | 0.00213 | uM | 7857.001 | 1.0074 | 1.0125 | 1.1724 | |
| HCC70 | TNBC | Basal A | GSK1070916 | AURK | AURK | 0.0107 | uM | 7857.001 | 0.9343 | 0.8873 | 1.1724 | |
| HCC70 | TNBC | Basal A | GSK1070916 | AURK | AURK | 0.0533 | uM | 7857.001 | 0.7334 | 0.5352 | 1.1724 | |
| HCC70 | TNBC | Basal A | GSK1070916 | AURK | AURK | 0.267 | uM | 7857.001 | 0.6954 | 0.4671 | 1.1724 | |
| HCC70 | TNBC | Basal A | GSK1070916 | AURK | AURK | 1.33 | uM | 7857.001 | 0.5865 | 0.2687 | 1.1724 | |
| HCC70 | TNBC | Basal A | GSK1070916 | AURK | AURK | 6.67 | uM | 7857.001 | 0.4322 | -0.0222 | 1.1724 | |
| HCC70 | TNBC | Basal A | GSK1070916 | AURK | AURK | 33.3 | uM | 7857.001 | 0.0750 | -0.7804 | 1.1724 |