Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UACC-893 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 0.000427 | uM | 9045.016 | 1.1868 | 1.4180 | 0.9026 | |
| UACC-893 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 0.00213 | uM | 9045.016 | 0.8889 | 0.7553 | 0.9026 | |
| UACC-893 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 0.0107 | uM | 9045.016 | 1.0125 | 1.0276 | 0.9026 | |
| UACC-893 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 0.0533 | uM | 9045.016 | 1.0921 | 1.2051 | 0.9026 | |
| UACC-893 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 0.267 | uM | 9045.016 | 1.0287 | 1.0636 | 0.9026 | |
| UACC-893 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 1.33 | uM | 9045.016 | 0.8569 | 0.6854 | 0.9026 | |
| UACC-893 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 6.67 | uM | 9045.016 | 0.9274 | 0.8397 | 0.9026 | |
| UACC-893 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 33.3 | uM | 9045.016 | 0.4430 | -0.1885 | 0.9026 | |
| UACC-893 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 0.0000853 | uM | 9953.049 | 1.2400 | 1.9765 | 0.5411 | |
| UACC-893 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 0.000427 | uM | 9953.049 | 0.8938 | 0.6254 | 0.5411 | |
| UACC-893 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 0.00213 | uM | 9953.049 | 1.2211 | 1.8930 | 0.5411 | |
| UACC-893 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 0.0107 | uM | 9953.049 | 1.0217 | 1.0808 | 0.5411 | |
| UACC-893 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 0.0533 | uM | 9953.049 | 1.1184 | 1.4597 | 0.5411 | |
| UACC-893 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 0.267 | uM | 9953.049 | 0.9143 | 0.6947 | 0.5411 | |
| UACC-893 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 1.33 | uM | 9953.049 | 0.8474 | 0.4728 | 0.5411 | |
| UACC-893 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 6.67 | uM | 9953.049 | 0.7085 | 0.0579 | 0.5411 | |
| UACC-893 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 33.3 | uM | 9953.049 | 0.4009 | -0.6307 | 0.5411 | |
| ZR-75-1 | HR+ | Luminal | Gefitinib | EGFR | ErbB | 0.0000853 | uM | 7931.016 | 0.9866 | 0.9796 | 1.3152 | |
| ZR-75-1 | HR+ | Luminal | Gefitinib | EGFR | ErbB | 0.000427 | uM | 7931.016 | 0.9737 | 0.9599 | 1.3152 | |
| ZR-75-1 | HR+ | Luminal | Gefitinib | EGFR | ErbB | 0.00213 | uM | 7931.016 | 0.9797 | 0.9690 | 1.3152 | |
| ZR-75-1 | HR+ | Luminal | Gefitinib | EGFR | ErbB | 0.0107 | uM | 7931.016 | 0.9900 | 0.9847 | 1.3152 | |
| ZR-75-1 | HR+ | Luminal | Gefitinib | EGFR | ErbB | 0.0533 | uM | 7931.016 | 0.9730 | 0.9588 | 1.3152 | |
| ZR-75-1 | HR+ | Luminal | Gefitinib | EGFR | ErbB | 0.267 | uM | 7931.016 | 1.0005 | 1.0008 | 1.3152 | |
| ZR-75-1 | HR+ | Luminal | Gefitinib | EGFR | ErbB | 1.33 | uM | 7931.016 | 0.9318 | 0.8954 | 1.3152 | |
| ZR-75-1 | HR+ | Luminal | Gefitinib | EGFR | ErbB | 6.67 | uM | 7931.016 | 0.9106 | 0.8626 | 1.3152 |