Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-231 | TNBC | Basal B | Gefitinib | EGFR | ErbB | 0.0533 | uM | 7892.016 | 0.9936 | 0.9945 | 2.3475 | |
| MDA-MB-231 | TNBC | Basal B | Gefitinib | EGFR | ErbB | 0.267 | uM | 7892.016 | 1.0349 | 1.0294 | 2.3475 | |
| MDA-MB-231 | TNBC | Basal B | Gefitinib | EGFR | ErbB | 1.33 | uM | 7892.016 | 1.0051 | 1.0043 | 2.3475 | |
| MDA-MB-231 | TNBC | Basal B | Gefitinib | EGFR | ErbB | 6.67 | uM | 7892.016 | 0.8999 | 0.9122 | 2.3475 | |
| MDA-MB-231 | TNBC | Basal B | Gefitinib | EGFR | ErbB | 33.3 | uM | 7892.016 | 0.7948 | 0.8136 | 2.3475 | |
| MDA-MB-231 | TNBC | Basal B | Gefitinib | EGFR | ErbB | 0.0000853 | uM | 7893.016 | 1.0184 | 1.0166 | 2.2064 | |
| MDA-MB-231 | TNBC | Basal B | Gefitinib | EGFR | ErbB | 0.000427 | uM | 7893.016 | 1.0064 | 1.0058 | 2.2064 | |
| MDA-MB-231 | TNBC | Basal B | Gefitinib | EGFR | ErbB | 0.00213 | uM | 7893.016 | 1.0698 | 1.0621 | 2.2064 | |
| MDA-MB-231 | TNBC | Basal B | Gefitinib | EGFR | ErbB | 0.0107 | uM | 7893.016 | 1.0492 | 1.0440 | 2.2064 | |
| MDA-MB-231 | TNBC | Basal B | Gefitinib | EGFR | ErbB | 0.0533 | uM | 7893.016 | 1.0202 | 1.0182 | 2.2064 | |
| MDA-MB-231 | TNBC | Basal B | Gefitinib | EGFR | ErbB | 0.267 | uM | 7893.016 | 0.9874 | 0.9885 | 2.2064 | |
| MDA-MB-231 | TNBC | Basal B | Gefitinib | EGFR | ErbB | 1.33 | uM | 7893.016 | 1.0245 | 1.0221 | 2.2064 | |
| MDA-MB-231 | TNBC | Basal B | Gefitinib | EGFR | ErbB | 6.67 | uM | 7893.016 | 0.9461 | 0.9504 | 2.2064 | |
| MDA-MB-231 | TNBC | Basal B | Gefitinib | EGFR | ErbB | 33.3 | uM | 7893.016 | 0.8337 | 0.8417 | 2.2064 | |
| MDA-MB-361 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 0.0000853 | uM | 7505.016 | 0.9953 | 0.9912 | 1.0721 | |
| MDA-MB-361 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 0.000427 | uM | 7505.016 | 1.0095 | 1.0178 | 1.0721 | |
| MDA-MB-361 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 0.00213 | uM | 7505.016 | 0.9961 | 0.9926 | 1.0721 | |
| MDA-MB-361 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 0.0107 | uM | 7505.016 | 0.9999 | 0.9998 | 1.0721 | |
| MDA-MB-361 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 0.0533 | uM | 7505.016 | 1.0202 | 1.0377 | 1.0721 | |
| MDA-MB-361 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 0.267 | uM | 7505.016 | 0.9714 | 0.9466 | 1.0721 | |
| MDA-MB-361 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 1.33 | uM | 7505.016 | 0.9619 | 0.9289 | 1.0721 | |
| MDA-MB-361 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 6.67 | uM | 7505.016 | 0.7914 | 0.6079 | 1.0721 | |
| MDA-MB-361 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 33.3 | uM | 7505.016 | 0.6303 | 0.3003 | 1.0721 | |
| MDA-MB-361 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 0.0000853 | uM | 7894.016 | 1.0430 | 1.1116 | 0.7753 | |
| MDA-MB-361 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 0.000427 | uM | 7894.016 | 0.9699 | 0.9227 | 0.7753 |