Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1806 | TNBC | Basal A | Gefitinib | EGFR | ErbB | 1.33 | uM | 9376.049 | 0.7913 | 0.7708 | 1.9229 | |
| HCC1806 | TNBC | Basal A | Gefitinib | EGFR | ErbB | 6.67 | uM | 9376.049 | 0.7049 | 0.6674 | 1.9229 | |
| HCC1806 | TNBC | Basal A | Gefitinib | EGFR | ErbB | 33.3 | uM | 9376.049 | 0.5774 | 0.5031 | 1.9229 | |
| HCC1937 | TNBC | Basal A | Gefitinib | EGFR | ErbB | 0.0000853 | uM | 7832.016 | 1.0254 | 1.0403 | 1.2588 | |
| HCC1937 | TNBC | Basal A | Gefitinib | EGFR | ErbB | 0.000427 | uM | 7832.016 | 0.9953 | 0.9925 | 1.2588 | |
| HCC1937 | TNBC | Basal A | Gefitinib | EGFR | ErbB | 0.00213 | uM | 7832.016 | 1.0473 | 1.0747 | 1.2588 | |
| HCC1937 | TNBC | Basal A | Gefitinib | EGFR | ErbB | 0.0107 | uM | 7832.016 | 1.0446 | 1.0705 | 1.2588 | |
| HCC1937 | TNBC | Basal A | Gefitinib | EGFR | ErbB | 0.0533 | uM | 7832.016 | 1.0112 | 1.0178 | 1.2588 | |
| HCC1937 | TNBC | Basal A | Gefitinib | EGFR | ErbB | 0.267 | uM | 7832.016 | 0.9093 | 0.8545 | 1.2588 | |
| HCC1937 | TNBC | Basal A | Gefitinib | EGFR | ErbB | 1.33 | uM | 7832.016 | 0.8762 | 0.8006 | 1.2588 | |
| HCC1937 | TNBC | Basal A | Gefitinib | EGFR | ErbB | 6.67 | uM | 7832.016 | 0.7990 | 0.6734 | 1.2588 | |
| HCC1937 | TNBC | Basal A | Gefitinib | EGFR | ErbB | 33.3 | uM | 7832.016 | 0.3202 | -0.1907 | 1.2588 | |
| HCC1937 | TNBC | Basal A | Gefitinib | EGFR | ErbB | 0.0000853 | uM | 7834.016 | 1.0292 | 1.0284 | 2.0442 | |
| HCC1937 | TNBC | Basal A | Gefitinib | EGFR | ErbB | 0.000427 | uM | 7834.016 | 1.0506 | 1.0489 | 2.0442 | |
| HCC1937 | TNBC | Basal A | Gefitinib | EGFR | ErbB | 0.00213 | uM | 7834.016 | 0.9221 | 0.9222 | 2.0442 | |
| HCC1937 | TNBC | Basal A | Gefitinib | EGFR | ErbB | 0.0107 | uM | 7834.016 | 1.0371 | 1.0360 | 2.0442 | |
| HCC1937 | TNBC | Basal A | Gefitinib | EGFR | ErbB | 0.0533 | uM | 7834.016 | 0.9534 | 0.9539 | 2.0442 | |
| HCC1937 | TNBC | Basal A | Gefitinib | EGFR | ErbB | 0.267 | uM | 7834.016 | 0.8206 | 0.8156 | 2.0442 | |
| HCC1937 | TNBC | Basal A | Gefitinib | EGFR | ErbB | 1.33 | uM | 7834.016 | 0.7952 | 0.7879 | 2.0442 | |
| HCC1937 | TNBC | Basal A | Gefitinib | EGFR | ErbB | 6.67 | uM | 7834.016 | 0.7633 | 0.7525 | 2.0442 | |
| HCC1937 | TNBC | Basal A | Gefitinib | EGFR | ErbB | 33.3 | uM | 7834.016 | 0.3437 | 0.1862 | 2.0442 | |
| HCC1954 | HER2amp | Basal A | Gefitinib | EGFR | ErbB | 0.0000853 | uM | 7836.016 | 0.9765 | 0.9699 | 1.5669 | |
| HCC1954 | HER2amp | Basal A | Gefitinib | EGFR | ErbB | 0.000427 | uM | 7836.016 | 1.0219 | 1.0279 | 1.5669 | |
| HCC1954 | HER2amp | Basal A | Gefitinib | EGFR | ErbB | 0.00213 | uM | 7836.016 | 0.9035 | 0.8745 | 1.5669 | |
| HCC1954 | HER2amp | Basal A | Gefitinib | EGFR | ErbB | 0.0107 | uM | 7836.016 | 1.0753 | 1.0948 | 1.5669 |