Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC70 | TNBC | Basal A | Fascaplysin | CDK4 | CDK | 1.33 | uM | 7470.085 | 0.0212 | -0.9596 | 0.9880 | |
| HCC70 | TNBC | Basal A | Fascaplysin | CDK4 | CDK | 6.67 | uM | 7470.085 | 0.0161 | -0.9694 | 0.9880 | |
| HCC70 | TNBC | Basal A | Fascaplysin | CDK4 | CDK | 33.3 | uM | 7470.085 | 0.0123 | -0.9766 | 0.9880 | |
| Hs 578T | TNBC | Basal B | Fascaplysin | CDK4 | CDK | 0.0000853 | uM | 7473.084 | 0.9732 | 0.9734 | 2.0337 | |
| Hs 578T | TNBC | Basal B | Fascaplysin | CDK4 | CDK | 0.000427 | uM | 7473.084 | 1.0632 | 1.0612 | 2.0337 | |
| Hs 578T | TNBC | Basal B | Fascaplysin | CDK4 | CDK | 0.00213 | uM | 7473.084 | 1.0552 | 1.0536 | 2.0337 | |
| Hs 578T | TNBC | Basal B | Fascaplysin | CDK4 | CDK | 0.0107 | uM | 7473.084 | 1.0975 | 1.0937 | 2.0337 | |
| Hs 578T | TNBC | Basal B | Fascaplysin | CDK4 | CDK | 0.0533 | uM | 7473.084 | 1.1620 | 1.1533 | 2.0337 | |
| Hs 578T | TNBC | Basal B | Fascaplysin | CDK4 | CDK | 0.267 | uM | 7473.084 | 1.9299 | 1.7634 | 2.0337 | |
| Hs 578T | TNBC | Basal B | Fascaplysin | CDK4 | CDK | 1.33 | uM | 7473.084 | 0.1580 | -0.1927 | 2.0337 | |
| Hs 578T | TNBC | Basal B | Fascaplysin | CDK4 | CDK | 6.67 | uM | 7473.084 | 0.0324 | -0.6297 | 2.0337 | |
| Hs 578T | TNBC | Basal B | Fascaplysin | CDK4 | CDK | 33.3 | uM | 7473.084 | 0.0008 | -0.9410 | 2.0337 | |
| Hs 578T | TNBC | Basal B | Fascaplysin | CDK4 | CDK | 0.0000853 | uM | 7474.084 | 1.0274 | 1.0204 | 2.6631 | |
| Hs 578T | TNBC | Basal B | Fascaplysin | CDK4 | CDK | 0.000427 | uM | 7474.084 | 0.9106 | 0.9309 | 2.6631 | |
| Hs 578T | TNBC | Basal B | Fascaplysin | CDK4 | CDK | 0.00213 | uM | 7474.084 | 0.8685 | 0.8969 | 2.6631 | |
| Hs 578T | TNBC | Basal B | Fascaplysin | CDK4 | CDK | 0.0107 | uM | 7474.084 | 1.2068 | 1.1463 | 2.6631 | |
| Hs 578T | TNBC | Basal B | Fascaplysin | CDK4 | CDK | 0.0533 | uM | 7474.084 | 1.2015 | 1.1427 | 2.6631 | |
| Hs 578T | TNBC | Basal B | Fascaplysin | CDK4 | CDK | 0.267 | uM | 7474.084 | 1.2559 | 1.1786 | 2.6631 | |
| Hs 578T | TNBC | Basal B | Fascaplysin | CDK4 | CDK | 1.33 | uM | 7474.084 | 0.0382 | -0.4129 | 2.6631 | |
| Hs 578T | TNBC | Basal B | Fascaplysin | CDK4 | CDK | 6.67 | uM | 7474.084 | 0.0107 | -0.6359 | 2.6631 | |
| Hs 578T | TNBC | Basal B | Fascaplysin | CDK4 | CDK | 33.3 | uM | 7474.084 | 0.0007 | -0.8699 | 2.6631 | |
| Hs 578T | TNBC | Basal B | Fascaplysin | CDK4 | CDK | 0.0000853 | uM | 7475.084 | 1.1642 | 1.1124 | 2.7804 | |
| Hs 578T | TNBC | Basal B | Fascaplysin | CDK4 | CDK | 0.000427 | uM | 7475.084 | 1.0408 | 1.0290 | 2.7804 | |
| Hs 578T | TNBC | Basal B | Fascaplysin | CDK4 | CDK | 0.00213 | uM | 7475.084 | 1.1161 | 1.0806 | 2.7804 | |
| Hs 578T | TNBC | Basal B | Fascaplysin | CDK4 | CDK | 0.0107 | uM | 7475.084 | 1.1327 | 1.0916 | 2.7804 |