Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC2185 | TNBC | Luminal | Fascaplysin | CDK4 | CDK | 0.000427 | uM | 7464.084 | 0.9625 | 0.9084 | 0.8152 | |
| HCC2185 | TNBC | Luminal | Fascaplysin | CDK4 | CDK | 0.00213 | uM | 7464.084 | 0.9993 | 0.9983 | 0.8152 | |
| HCC2185 | TNBC | Luminal | Fascaplysin | CDK4 | CDK | 0.0107 | uM | 7464.084 | 1.0085 | 1.0209 | 0.8152 | |
| HCC2185 | TNBC | Luminal | Fascaplysin | CDK4 | CDK | 0.0533 | uM | 7464.084 | 0.8873 | 0.7272 | 0.8152 | |
| HCC2185 | TNBC | Luminal | Fascaplysin | CDK4 | CDK | 0.267 | uM | 7464.084 | 0.5672 | -0.0025 | 0.8152 | |
| HCC2185 | TNBC | Luminal | Fascaplysin | CDK4 | CDK | 1.33 | uM | 7464.084 | 0.0081 | -0.9946 | 0.8152 | |
| HCC2185 | TNBC | Luminal | Fascaplysin | CDK4 | CDK | 6.67 | uM | 7464.084 | 0.0100 | -0.9929 | 0.8152 | |
| HCC2185 | TNBC | Luminal | Fascaplysin | CDK4 | CDK | 33.3 | uM | 7464.084 | 0.0066 | -0.9958 | 0.8152 | |
| HCC3153 | TNBC | Basal A | Fascaplysin | CDK4 | CDK | 0.0000853 | uM | 7466.085 | 1.0144 | 1.0332 | 0.8684 | |
| HCC3153 | TNBC | Basal A | Fascaplysin | CDK4 | CDK | 0.000427 | uM | 7466.085 | 0.9523 | 0.8905 | 0.8684 | |
| HCC3153 | TNBC | Basal A | Fascaplysin | CDK4 | CDK | 0.00213 | uM | 7466.085 | 0.9660 | 0.9219 | 0.8684 | |
| HCC3153 | TNBC | Basal A | Fascaplysin | CDK4 | CDK | 0.0107 | uM | 7466.085 | 0.9596 | 0.9073 | 0.8684 | |
| HCC3153 | TNBC | Basal A | Fascaplysin | CDK4 | CDK | 0.0533 | uM | 7466.085 | 0.9228 | 0.8233 | 0.8684 | |
| HCC3153 | TNBC | Basal A | Fascaplysin | CDK4 | CDK | 0.267 | uM | 7466.085 | 0.9185 | 0.8135 | 0.8684 | |
| HCC3153 | TNBC | Basal A | Fascaplysin | CDK4 | CDK | 1.33 | uM | 7466.085 | 0.3009 | -0.4984 | 0.8684 | |
| HCC3153 | TNBC | Basal A | Fascaplysin | CDK4 | CDK | 6.67 | uM | 7466.085 | 0.0122 | -0.9875 | 0.8684 | |
| HCC3153 | TNBC | Basal A | Fascaplysin | CDK4 | CDK | 33.3 | uM | 7466.085 | 0.0083 | -0.9920 | 0.8684 | |
| HCC3153 | TNBC | Basal A | Fascaplysin | CDK4 | CDK | 0.0000853 | uM | 7467.084 | 0.9997 | 0.9995 | 1.3029 | |
| HCC3153 | TNBC | Basal A | Fascaplysin | CDK4 | CDK | 0.000427 | uM | 7467.084 | 0.9639 | 0.9444 | 1.3029 | |
| HCC3153 | TNBC | Basal A | Fascaplysin | CDK4 | CDK | 0.00213 | uM | 7467.084 | 0.9968 | 0.9950 | 1.3029 | |
| HCC3153 | TNBC | Basal A | Fascaplysin | CDK4 | CDK | 0.0107 | uM | 7467.084 | 0.9847 | 0.9765 | 1.3029 | |
| HCC3153 | TNBC | Basal A | Fascaplysin | CDK4 | CDK | 0.0533 | uM | 7467.084 | 0.9375 | 0.9033 | 1.3029 | |
| HCC3153 | TNBC | Basal A | Fascaplysin | CDK4 | CDK | 0.267 | uM | 7467.084 | 0.3441 | -0.1180 | 1.3029 | |
| HCC3153 | TNBC | Basal A | Fascaplysin | CDK4 | CDK | 1.33 | uM | 7467.084 | 0.0072 | -0.9546 | 1.3029 | |
| HCC3153 | TNBC | Basal A | Fascaplysin | CDK4 | CDK | 6.67 | uM | 7467.084 | 0.0128 | -0.9293 | 1.3029 |