Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
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T47DKBLUC | Unknown | Unknown | Everolimus | MTOR | MTOR | 2.67 | uM | 12608.164 | 0.7630 | 0.5655 | 1.1044 | |
T47DKBLUC | Unknown | Unknown | Everolimus | MTOR | MTOR | 13.3 | uM | 12608.164 | 0.7803 | 0.5977 | 1.1044 | |
T47DKBLUC | Unknown | Unknown | Everolimus | MTOR | MTOR | 66.7 | uM | 12608.164 | 0.2903 | -0.3473 | 1.1044 | |
UACC-812 | HER2amp | Luminal | Everolimus | MTOR | MTOR | 0.000171 | uM | 11938.164 | 0.9290 | 0.8031 | 0.7111 | |
UACC-812 | HER2amp | Luminal | Everolimus | MTOR | MTOR | 0.000853 | uM | 11938.164 | 0.8573 | 0.6107 | 0.7111 | |
UACC-812 | HER2amp | Luminal | Everolimus | MTOR | MTOR | 0.00427 | uM | 11938.164 | 0.8836 | 0.6805 | 0.7111 | |
UACC-812 | HER2amp | Luminal | Everolimus | MTOR | MTOR | 0.0213 | uM | 11938.164 | 0.8022 | 0.4669 | 0.7111 | |
UACC-812 | HER2amp | Luminal | Everolimus | MTOR | MTOR | 0.107 | uM | 11938.164 | 0.7660 | 0.3748 | 0.7111 | |
UACC-812 | HER2amp | Luminal | Everolimus | MTOR | MTOR | 0.533 | uM | 11938.164 | 0.7077 | 0.2300 | 0.7111 | |
UACC-812 | HER2amp | Luminal | Everolimus | MTOR | MTOR | 2.67 | uM | 11938.164 | 0.6530 | 0.0984 | 0.7111 | |
UACC-812 | HER2amp | Luminal | Everolimus | MTOR | MTOR | 13.3 | uM | 11938.164 | 0.7484 | 0.3305 | 0.7111 | |
UACC-812 | HER2amp | Luminal | Everolimus | MTOR | MTOR | 66.7 | uM | 11938.164 | 0.5492 | -0.1389 | 0.7111 | |
ZR-75-1 | HR+ | Luminal | Everolimus | MTOR | MTOR | 0.000171 | uM | 12003.164 | 0.9684 | 0.9336 | 0.9505 | |
ZR-75-1 | HR+ | Luminal | Everolimus | MTOR | MTOR | 0.000853 | uM | 12003.164 | 0.9260 | 0.8447 | 0.9505 | |
ZR-75-1 | HR+ | Luminal | Everolimus | MTOR | MTOR | 0.00427 | uM | 12003.164 | 0.9310 | 0.8550 | 0.9505 | |
ZR-75-1 | HR+ | Luminal | Everolimus | MTOR | MTOR | 0.0213 | uM | 12003.164 | 0.7415 | 0.4601 | 0.9505 | |
ZR-75-1 | HR+ | Luminal | Everolimus | MTOR | MTOR | 0.107 | uM | 12003.164 | 0.6361 | 0.2426 | 0.9505 | |
ZR-75-1 | HR+ | Luminal | Everolimus | MTOR | MTOR | 0.533 | uM | 12003.164 | 0.6082 | 0.1853 | 0.9505 | |
ZR-75-1 | HR+ | Luminal | Everolimus | MTOR | MTOR | 2.67 | uM | 12003.164 | 0.5451 | 0.0562 | 0.9505 | |
ZR-75-1 | HR+ | Luminal | Everolimus | MTOR | MTOR | 13.3 | uM | 12003.164 | 0.5374 | 0.0405 | 0.9505 | |
ZR-75-1 | HR+ | Luminal | Everolimus | MTOR | MTOR | 66.7 | uM | 12003.164 | 0.4545 | -0.1277 | 0.9505 | |
ZR75B | HR+ | Luminal | Everolimus | MTOR | MTOR | 0.000171 | uM | 11939.164 | 1.0044 | 1.0054 | 1.6455 | |
ZR75B | HR+ | Luminal | Everolimus | MTOR | MTOR | 0.000853 | uM | 11939.164 | 0.9172 | 0.8977 | 1.6455 | |
ZR75B | HR+ | Luminal | Everolimus | MTOR | MTOR | 0.00427 | uM | 11939.164 | 0.8921 | 0.8659 | 1.6455 | |
ZR75B | HR+ | Luminal | Everolimus | MTOR | MTOR | 0.0213 | uM | 11939.164 | 0.7647 | 0.6991 | 1.6455 |