Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset - HMS LINCS Database

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)

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Small molecules	Cells	Antibodies

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Cell	Clinical Subtype	Transcriptional Subtype	Small Molecule	Perturbagen Target	Perturbagen Class	Perturbagen Concentration	Perturbagen Conc Unit	Biological Replicate ID	Relative Cell Count	Normalized Growth Rate Inhibition Value	Nominal Division Rate
MDA-MB-436	TNBC	Basal B	GSK923295	CENPE	Kinesin	0.0533	uM	7902.001	0.6454	0.5951	1.9359
MDA-MB-436	TNBC	Basal B	GSK923295	CENPE	Kinesin	0.267	uM	7902.001	0.4241	0.2840	1.9359
MDA-MB-436	TNBC	Basal B	GSK923295	CENPE	Kinesin	1.33	uM	7902.001	0.5596	0.4819	1.9359
MDA-MB-436	TNBC	Basal B	GSK923295	CENPE	Kinesin	6.67	uM	7902.001	0.6072	0.5457	1.9359
MDA-MB-436	TNBC	Basal B	GSK923295	CENPE	Kinesin	33.3	uM	7902.001	0.3939	0.2360	1.9359
MDA-MB-436	TNBC	Basal B	GSK923295	CENPE	Kinesin	0.0000853	uM	10266.001	1.1600	1.4001	0.8138
MDA-MB-436	TNBC	Basal B	GSK923295	CENPE	Kinesin	0.000427	uM	10266.001	0.7873	0.4909	0.8138
MDA-MB-436	TNBC	Basal B	GSK923295	CENPE	Kinesin	0.00213	uM	10266.001	1.1183	1.2946	0.8138
MDA-MB-436	TNBC	Basal B	GSK923295	CENPE	Kinesin	0.0107	uM	10266.001	0.8321	0.5956	0.8138
MDA-MB-436	TNBC	Basal B	GSK923295	CENPE	Kinesin	0.0533	uM	10266.001	0.6040	0.0765	0.8138
MDA-MB-436	TNBC	Basal B	GSK923295	CENPE	Kinesin	0.267	uM	10266.001	0.4999	-0.1469	0.8138
MDA-MB-436	TNBC	Basal B	GSK923295	CENPE	Kinesin	1.33	uM	10266.001	0.6005	0.0688	0.8138
MDA-MB-436	TNBC	Basal B	GSK923295	CENPE	Kinesin	6.67	uM	10266.001	0.6404	0.1567	0.8138
MDA-MB-436	TNBC	Basal B	GSK923295	CENPE	Kinesin	33.3	uM	10266.001	0.4782	-0.1922	0.8138
MDA-MB-453	TNBC	Luminal	GSK923295	CENPE	Kinesin	0.0000853	uM	9708.001	1.0608	1.1199	1.0142
MDA-MB-453	TNBC	Luminal	GSK923295	CENPE	Kinesin	0.000427	uM	9708.001	1.1105	1.2177	1.0142
MDA-MB-453	TNBC	Luminal	GSK923295	CENPE	Kinesin	0.00213	uM	9708.001	1.0079	1.0156	1.0142
MDA-MB-453	TNBC	Luminal	GSK923295	CENPE	Kinesin	0.0107	uM	9708.001	1.0490	1.0965	1.0142
MDA-MB-453	TNBC	Luminal	GSK923295	CENPE	Kinesin	0.0533	uM	9708.001	0.5566	0.1223	1.0142
MDA-MB-453	TNBC	Luminal	GSK923295	CENPE	Kinesin	0.267	uM	9708.001	0.4002	-0.1893	1.0142
MDA-MB-453	TNBC	Luminal	GSK923295	CENPE	Kinesin	1.33	uM	9708.001	0.4952	0.0002	1.0142
MDA-MB-453	TNBC	Luminal	GSK923295	CENPE	Kinesin	6.67	uM	9708.001	0.5962	0.2010	1.0142
MDA-MB-453	TNBC	Luminal	GSK923295	CENPE	Kinesin	33.3	uM	9708.001	0.4749	-0.0402	1.0142
MDA-MB-453	TNBC	Luminal	GSK923295	CENPE	Kinesin	0.0000853	uM	9723.001	1.0302	1.0644	0.9400
MDA-MB-453	TNBC	Luminal	GSK923295	CENPE	Kinesin	0.000427	uM	9723.001	0.9546	0.9036	0.9400
MDA-MB-453	TNBC	Luminal	GSK923295	CENPE	Kinesin	0.00213	uM	9723.001	1.0737	1.1572	0.9400
MDA-MB-453	TNBC	Luminal	GSK923295	CENPE	Kinesin	0.0107	uM	9723.001	0.9694	0.9349	0.9400
MDA-MB-453	TNBC	Luminal	GSK923295	CENPE	Kinesin	0.0533	uM	9723.001	1.0465	1.0991	0.9400
MDA-MB-453	TNBC	Luminal	GSK923295	CENPE	Kinesin	0.267	uM	9723.001	0.3965	-0.2526	0.9400
MDA-MB-453	TNBC	Luminal	GSK923295	CENPE	Kinesin	1.33	uM	9723.001	0.5336	0.0253	0.9400
MDA-MB-453	TNBC	Luminal	GSK923295	CENPE	Kinesin	6.67	uM	9723.001	0.6767	0.3201	0.9400
MDA-MB-453	TNBC	Luminal	GSK923295	CENPE	Kinesin	33.3	uM	9723.001	0.5841	0.1288	0.9400
MDA-MB-468	TNBC	Basal A	GSK923295	CENPE	Kinesin	0.0000853	uM	7904.001	1.0712	1.1014	1.3917
MDA-MB-468	TNBC	Basal A	GSK923295	CENPE	Kinesin	0.000427	uM	7904.001	0.8643	0.8011	1.3917
MDA-MB-468	TNBC	Basal A	GSK923295	CENPE	Kinesin	0.00213	uM	7904.001	1.0651	1.0927	1.3917
MDA-MB-468	TNBC	Basal A	GSK923295	CENPE	Kinesin	0.0107	uM	7904.001	0.7405	0.6117	1.3917
MDA-MB-468	TNBC	Basal A	GSK923295	CENPE	Kinesin	0.0533	uM	7904.001	0.2916	-0.1751	1.3917
MDA-MB-468	TNBC	Basal A	GSK923295	CENPE	Kinesin	0.267	uM	7904.001	0.1167	-0.5729	1.3917
MDA-MB-468	TNBC	Basal A	GSK923295	CENPE	Kinesin	1.33	uM	7904.001	0.1843	-0.4068	1.3917
MDA-MB-468	TNBC	Basal A	GSK923295	CENPE	Kinesin	6.67	uM	7904.001	0.2013	-0.3680	1.3917
MDA-MB-468	TNBC	Basal A	GSK923295	CENPE	Kinesin	33.3	uM	7904.001	0.1396	-0.5140	1.3917
MDA-MB-468	TNBC	Basal A	GSK923295	CENPE	Kinesin	0.0000853	uM	7905.001	1.0691	1.1882	0.7433
MDA-MB-468	TNBC	Basal A	GSK923295	CENPE	Kinesin	0.000427	uM	7905.001	0.7887	0.4532	0.7433
MDA-MB-468	TNBC	Basal A	GSK923295	CENPE	Kinesin	0.00213	uM	7905.001	1.1230	1.3378	0.7433
MDA-MB-468	TNBC	Basal A	GSK923295	CENPE	Kinesin	0.0107	uM	7905.001	0.8675	0.6519	0.7433
MDA-MB-468	TNBC	Basal A	GSK923295	CENPE	Kinesin	0.0533	uM	7905.001	0.1187	-0.8863	0.7433
MDA-MB-468	TNBC	Basal A	GSK923295	CENPE	Kinesin	0.267	uM	7905.001	0.0733	-0.9406	0.7433
MDA-MB-468	TNBC	Basal A	GSK923295	CENPE	Kinesin	1.33	uM	7905.001	0.0996	-0.9102	0.7433
MDA-MB-468	TNBC	Basal A	GSK923295	CENPE	Kinesin	6.67	uM	7905.001	0.1343	-0.8657	0.7433
MDA-MB-468	TNBC	Basal A	GSK923295	CENPE	Kinesin	33.3	uM	7905.001	0.1151	-0.8909	0.7433

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HMS LINCS Project

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)