Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 184A1 | NM | Basal | (Z)-4-Hydroxytamoxifen | ESR1 | 0.000427 | uM | 9047.132 | 1.0270 | 1.0778 | 0.6985 | ||
| 184A1 | NM | Basal | (Z)-4-Hydroxytamoxifen | ESR1 | 0.00213 | uM | 9047.132 | 0.9693 | 0.9128 | 0.6985 | ||
| 184A1 | NM | Basal | (Z)-4-Hydroxytamoxifen | ESR1 | 0.0107 | uM | 9047.132 | 0.8736 | 0.6481 | 0.6985 | ||
| 184A1 | NM | Basal | (Z)-4-Hydroxytamoxifen | ESR1 | 0.0533 | uM | 9047.132 | 0.9788 | 0.9394 | 0.6985 | ||
| 184A1 | NM | Basal | (Z)-4-Hydroxytamoxifen | ESR1 | 0.267 | uM | 9047.132 | 0.9995 | 0.9985 | 0.6985 | ||
| 184A1 | NM | Basal | (Z)-4-Hydroxytamoxifen | ESR1 | 1.33 | uM | 9047.132 | 0.9661 | 0.9036 | 0.6985 | ||
| 184A1 | NM | Basal | (Z)-4-Hydroxytamoxifen | ESR1 | 6.67 | uM | 9047.132 | 0.8373 | 0.5511 | 0.6985 | ||
| 184A1 | NM | Basal | (Z)-4-Hydroxytamoxifen | ESR1 | 33.3 | uM | 9047.132 | 0.7816 | 0.4055 | 0.6985 | ||
| 184A1 | NM | Basal | (Z)-4-Hydroxytamoxifen | ESR1 | 167 | uM | 9047.132 | 0.9698 | 0.9141 | 0.6985 | ||
| 600MPE | HR+ | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 0.000427 | uM | 7791.016 | 1.0572 | 1.1416 | 0.8138 | ||
| 600MPE | HR+ | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 0.00213 | uM | 7791.016 | 1.0245 | 1.0604 | 0.8138 | ||
| 600MPE | HR+ | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 0.0107 | uM | 7791.016 | 1.0744 | 1.1842 | 0.8138 | ||
| 600MPE | HR+ | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 0.0533 | uM | 7791.016 | 1.0302 | 1.0745 | 0.8138 | ||
| 600MPE | HR+ | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 0.267 | uM | 7791.016 | 1.0193 | 1.0476 | 0.8138 | ||
| 600MPE | HR+ | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 1.33 | uM | 7791.016 | 1.0196 | 1.0483 | 0.8138 | ||
| 600MPE | HR+ | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 6.67 | uM | 7791.016 | 1.0201 | 1.0496 | 0.8138 | ||
| 600MPE | HR+ | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 33.3 | uM | 7791.016 | 0.7533 | 0.4121 | 0.8138 | ||
| 600MPE | HR+ | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 167 | uM | 7791.016 | 0.6272 | 0.1274 | 0.8138 | ||
| 600MPE | HR+ | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 0.000427 | uM | 9118.019 | 1.0600 | 1.1119 | 1.0707 | ||
| 600MPE | HR+ | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 0.00213 | uM | 9118.019 | 1.0577 | 1.1076 | 1.0707 | ||
| 600MPE | HR+ | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 0.0107 | uM | 9118.019 | 1.0672 | 1.1253 | 1.0707 | ||
| 600MPE | HR+ | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 0.0533 | uM | 9118.019 | 1.0092 | 1.0172 | 1.0707 | ||
| 600MPE | HR+ | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 0.267 | uM | 9118.019 | 1.0546 | 1.1018 | 1.0707 | ||
| 600MPE | HR+ | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 1.33 | uM | 9118.019 | 1.0516 | 1.0961 | 1.0707 | ||
| 600MPE | HR+ | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 6.67 | uM | 9118.019 | 0.9670 | 0.9382 | 1.0707 |