Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM1315MO2 | TNBC | Basal B | Etoposide | TOP2 | TOP | 0.0213 | uM | 7528.074 | 0.9699 | 0.9406 | 1.0143 | |
| SUM1315MO2 | TNBC | Basal B | Etoposide | TOP2 | TOP | 0.107 | uM | 7528.074 | 0.8766 | 0.7565 | 1.0143 | |
| SUM1315MO2 | TNBC | Basal B | Etoposide | TOP2 | TOP | 0.533 | uM | 7528.074 | 0.6020 | 0.2126 | 1.0143 | |
| SUM1315MO2 | TNBC | Basal B | Etoposide | TOP2 | TOP | 2.67 | uM | 7528.074 | 0.6226 | 0.2536 | 1.0143 | |
| SUM1315MO2 | TNBC | Basal B | Etoposide | TOP2 | TOP | 13.3 | uM | 7528.074 | 0.4115 | -0.1666 | 1.0143 | |
| SUM1315MO2 | TNBC | Basal B | Etoposide | TOP2 | TOP | 66.7 | uM | 7528.074 | 0.2566 | -0.4769 | 1.0143 | |
| SUM1315MO2 | TNBC | Basal B | Etoposide | TOP2 | TOP | 333 | uM | 7528.074 | 0.1560 | -0.6798 | 1.0143 | |
| SUM1315MO2 | TNBC | Basal B | Etoposide | TOP2 | TOP | 0.000853 | uM | 9044.074 | 0.9838 | 0.9513 | 0.6607 | |
| SUM1315MO2 | TNBC | Basal B | Etoposide | TOP2 | TOP | 0.00427 | uM | 9044.074 | 1.0104 | 1.0316 | 0.6607 | |
| SUM1315MO2 | TNBC | Basal B | Etoposide | TOP2 | TOP | 0.0213 | uM | 9044.074 | 1.0041 | 1.0123 | 0.6607 | |
| SUM1315MO2 | TNBC | Basal B | Etoposide | TOP2 | TOP | 0.107 | uM | 9044.074 | 0.8675 | 0.6129 | 0.6607 | |
| SUM1315MO2 | TNBC | Basal B | Etoposide | TOP2 | TOP | 0.533 | uM | 9044.074 | 0.5784 | -0.1266 | 0.6607 | |
| SUM1315MO2 | TNBC | Basal B | Etoposide | TOP2 | TOP | 2.67 | uM | 9044.074 | 0.5924 | -0.0946 | 0.6607 | |
| SUM1315MO2 | TNBC | Basal B | Etoposide | TOP2 | TOP | 13.3 | uM | 9044.074 | 0.4396 | -0.4235 | 0.6607 | |
| SUM1315MO2 | TNBC | Basal B | Etoposide | TOP2 | TOP | 66.7 | uM | 9044.074 | 0.3009 | -0.6752 | 0.6607 | |
| SUM1315MO2 | TNBC | Basal B | Etoposide | TOP2 | TOP | 333 | uM | 9044.074 | 0.2034 | -0.8205 | 0.6607 | |
| SUM149PT | TNBC | Basal B | Etoposide | TOP2 | TOP | 0.000853 | uM | 7530.074 | 1.0182 | 1.0173 | 2.0964 | |
| SUM149PT | TNBC | Basal B | Etoposide | TOP2 | TOP | 0.00427 | uM | 7530.074 | 0.9818 | 0.9826 | 2.0964 | |
| SUM149PT | TNBC | Basal B | Etoposide | TOP2 | TOP | 0.0213 | uM | 7530.074 | 0.9860 | 0.9866 | 2.0964 | |
| SUM149PT | TNBC | Basal B | Etoposide | TOP2 | TOP | 0.107 | uM | 7530.074 | 0.9367 | 0.9386 | 2.0964 | |
| SUM149PT | TNBC | Basal B | Etoposide | TOP2 | TOP | 0.533 | uM | 7530.074 | 0.6840 | 0.6686 | 2.0964 | |
| SUM149PT | TNBC | Basal B | Etoposide | TOP2 | TOP | 2.67 | uM | 7530.074 | 0.6177 | 0.5894 | 2.0964 | |
| SUM149PT | TNBC | Basal B | Etoposide | TOP2 | TOP | 13.3 | uM | 7530.074 | 0.4819 | 0.4119 | 2.0964 | |
| SUM149PT | TNBC | Basal B | Etoposide | TOP2 | TOP | 66.7 | uM | 7530.074 | 0.1130 | -0.2931 | 2.0964 | |
| SUM149PT | TNBC | Basal B | Etoposide | TOP2 | TOP | 333 | uM | 7530.074 | 0.0926 | -0.3573 | 2.0964 |