Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM52PE | HR+ | Luminal | Docetaxel | TUBB | TUBB | 10 | uM | 9878.002 | 0.3076 | -0.1683 | 1.3437 | |
| SUM52PE | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.0000256 | uM | 9889.002 | 0.9590 | 0.9307 | 1.1879 | |
| SUM52PE | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.000128 | uM | 9889.002 | 0.9616 | 0.9351 | 1.1879 | |
| SUM52PE | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.00064 | uM | 9889.002 | 0.8950 | 0.8216 | 1.1879 | |
| SUM52PE | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.0032 | uM | 9889.002 | 0.4318 | -0.0137 | 1.1879 | |
| SUM52PE | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.016 | uM | 9889.002 | 0.3059 | -0.2622 | 1.1879 | |
| SUM52PE | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.08 | uM | 9889.002 | 0.2523 | -0.3726 | 1.1879 | |
| SUM52PE | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.4 | uM | 9889.002 | 0.2445 | -0.3890 | 1.1879 | |
| SUM52PE | HR+ | Luminal | Docetaxel | TUBB | TUBB | 2 | uM | 9889.002 | 0.2574 | -0.3619 | 1.1879 | |
| SUM52PE | HR+ | Luminal | Docetaxel | TUBB | TUBB | 10 | uM | 9889.002 | 0.2979 | -0.2784 | 1.1879 | |
| SUM52PE | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.0000256 | uM | 12969.002 | 0.7970 | 0.6163 | 1.0653 | |
| SUM52PE | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.000128 | uM | 12969.002 | 1.0367 | 1.0688 | 1.0653 | |
| SUM52PE | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.00064 | uM | 12969.002 | 0.7191 | 0.4676 | 1.0653 | |
| SUM52PE | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.0032 | uM | 12969.002 | 0.7450 | 0.5171 | 1.0653 | |
| SUM52PE | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.016 | uM | 12969.002 | 0.6152 | 0.2676 | 1.0653 | |
| SUM52PE | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.08 | uM | 12969.002 | 0.6056 | 0.2491 | 1.0653 | |
| SUM52PE | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.4 | uM | 12969.002 | 0.5734 | 0.1865 | 1.0653 | |
| SUM52PE | HR+ | Luminal | Docetaxel | TUBB | TUBB | 2 | uM | 12969.002 | 0.5412 | 0.1240 | 1.0653 | |
| SUM52PE | HR+ | Luminal | Docetaxel | TUBB | TUBB | 10 | uM | 12969.002 | 0.5680 | 0.1760 | 1.0653 | |
| T47D | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.0000256 | uM | 9897.002 | 1.0268 | 1.1342 | 0.4068 | |
| T47D | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.000128 | uM | 9897.002 | 1.1152 | 1.6148 | 0.4068 | |
| T47D | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.00064 | uM | 9897.002 | 1.0740 | 1.3837 | 0.4068 | |
| T47D | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.0032 | uM | 9897.002 | 0.7790 | 0.0825 | 0.4068 | |
| T47D | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.016 | uM | 9897.002 | 0.5121 | -0.6141 | 0.4068 | |
| T47D | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.08 | uM | 9897.002 | 0.4963 | -0.6426 | 0.4068 |