Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC70 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 250 | uM | 7860.017 | 0.0088 | -0.9990 | 0.6196 | |
| HCC70 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 0.00064 | uM | 9501.03 | 1.0064 | 1.0185 | 0.6902 | |
| HCC70 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 0.0032 | uM | 9501.03 | 1.0310 | 1.0904 | 0.6902 | |
| HCC70 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 0.016 | uM | 9501.03 | 1.0666 | 1.1958 | 0.6902 | |
| HCC70 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 0.08 | uM | 9501.03 | 0.9869 | 0.9622 | 0.6902 | |
| HCC70 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 0.4 | uM | 9501.03 | 0.9926 | 0.9786 | 0.6902 | |
| HCC70 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 2 | uM | 9501.03 | 0.6808 | 0.1458 | 0.6902 | |
| HCC70 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 10 | uM | 9501.03 | 0.0165 | -0.9948 | 0.6902 | |
| HCC70 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 50 | uM | 9501.03 | 1.0406 | 1.1187 | 0.6902 | |
| HCC70 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 250 | uM | 9501.03 | 0.0063 | -0.9987 | 0.6902 | |
| HMT-3522 S1 | Unknown | Unknown | Cisplatin | DNA cross-linker | DNA cross-linker | 0.00064 | uM | 7911.017 | 1.0937 | 1.1140 | 1.6151 | |
| HMT-3522 S1 | Unknown | Unknown | Cisplatin | DNA cross-linker | DNA cross-linker | 0.0032 | uM | 7911.017 | 0.9455 | 0.9318 | 1.6151 | |
| HMT-3522 S1 | Unknown | Unknown | Cisplatin | DNA cross-linker | DNA cross-linker | 0.016 | uM | 7911.017 | 1.0914 | 1.1113 | 1.6151 | |
| HMT-3522 S1 | Unknown | Unknown | Cisplatin | DNA cross-linker | DNA cross-linker | 0.08 | uM | 7911.017 | 1.0180 | 1.0222 | 1.6151 | |
| HMT-3522 S1 | Unknown | Unknown | Cisplatin | DNA cross-linker | DNA cross-linker | 0.4 | uM | 7911.017 | 1.0620 | 1.0759 | 1.6151 | |
| HMT-3522 S1 | Unknown | Unknown | Cisplatin | DNA cross-linker | DNA cross-linker | 2 | uM | 7911.017 | 0.8142 | 0.7610 | 1.6151 | |
| HMT-3522 S1 | Unknown | Unknown | Cisplatin | DNA cross-linker | DNA cross-linker | 10 | uM | 7911.017 | 0.4817 | 0.2724 | 1.6151 | |
| HMT-3522 S1 | Unknown | Unknown | Cisplatin | DNA cross-linker | DNA cross-linker | 50 | uM | 7911.017 | 0.0790 | -0.5846 | 1.6151 | |
| HMT-3522 S1 | Unknown | Unknown | Cisplatin | DNA cross-linker | DNA cross-linker | 250 | uM | 7911.017 | 0.2195 | -0.2179 | 1.6151 | |
| HMT-3522 S1 | Unknown | Unknown | Cisplatin | DNA cross-linker | DNA cross-linker | 0.00064 | uM | 10124.021 | 1.0088 | 1.0089 | 1.9744 | |
| HMT-3522 S1 | Unknown | Unknown | Cisplatin | DNA cross-linker | DNA cross-linker | 0.0032 | uM | 10124.021 | 1.0462 | 1.0463 | 1.9744 | |
| HMT-3522 S1 | Unknown | Unknown | Cisplatin | DNA cross-linker | DNA cross-linker | 0.016 | uM | 10124.021 | 0.9936 | 0.9935 | 1.9744 | |
| HMT-3522 S1 | Unknown | Unknown | Cisplatin | DNA cross-linker | DNA cross-linker | 0.08 | uM | 10124.021 | 0.8735 | 0.8676 | 1.9744 | |
| HMT-3522 S1 | Unknown | Unknown | Cisplatin | DNA cross-linker | DNA cross-linker | 0.4 | uM | 10124.021 | 0.9069 | 0.9034 | 1.9744 | |
| HMT-3522 S1 | Unknown | Unknown | Cisplatin | DNA cross-linker | DNA cross-linker | 2 | uM | 10124.021 | 0.6844 | 0.6505 | 1.9744 |