Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1419 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 500 | uM | 10019.049 | 1.1184 | 1.5472 | 0.4626 | |
| HCC1428 | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.00064 | uM | 9294.017 | 1.0550 | 1.1357 | 0.8160 | |
| HCC1428 | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.0032 | uM | 9294.017 | 1.0296 | 1.0728 | 0.8160 | |
| HCC1428 | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.016 | uM | 9294.017 | 0.9961 | 0.9905 | 0.8160 | |
| HCC1428 | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.08 | uM | 9294.017 | 0.9945 | 0.9866 | 0.8160 | |
| HCC1428 | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.4 | uM | 9294.017 | 1.0315 | 1.0775 | 0.8160 | |
| HCC1428 | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 2 | uM | 9294.017 | 1.0468 | 1.1154 | 0.8160 | |
| HCC1428 | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 10 | uM | 9294.017 | 1.0259 | 1.0636 | 0.8160 | |
| HCC1428 | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 50 | uM | 9294.017 | 0.0685 | -0.9252 | 0.8160 | |
| HCC1428 | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 250 | uM | 9294.017 | 0.0241 | -0.9792 | 0.8160 | |
| HCC1428 | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.00064 | uM | 10031.021 | 1.1090 | 1.2606 | 0.8450 | |
| HCC1428 | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.0032 | uM | 10031.021 | 1.0023 | 1.0055 | 0.8450 | |
| HCC1428 | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.016 | uM | 10031.021 | 1.0796 | 1.1898 | 0.8450 | |
| HCC1428 | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.08 | uM | 10031.021 | 0.9490 | 0.8799 | 0.8450 | |
| HCC1428 | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.4 | uM | 10031.021 | 1.0000 | 0.9999 | 0.8450 | |
| HCC1428 | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 2 | uM | 10031.021 | 0.9723 | 0.9346 | 0.8450 | |
| HCC1428 | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 10 | uM | 10031.021 | 1.0769 | 1.1834 | 0.8450 | |
| HCC1428 | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 50 | uM | 10031.021 | 0.6730 | 0.2517 | 0.8450 | |
| HCC1428 | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 250 | uM | 10031.021 | 0.0643 | -0.9223 | 0.8450 | |
| HCC1569 | HER2amp | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 0.00064 | uM | 7824.017 | 0.9722 | 0.9665 | 1.6694 | |
| HCC1569 | HER2amp | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 0.0032 | uM | 7824.017 | 1.0188 | 1.0225 | 1.6694 | |
| HCC1569 | HER2amp | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 0.016 | uM | 7824.017 | 0.9563 | 0.9472 | 1.6694 | |
| HCC1569 | HER2amp | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 0.08 | uM | 7824.017 | 0.9127 | 0.8935 | 1.6694 | |
| HCC1569 | HER2amp | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 0.4 | uM | 7824.017 | 0.9355 | 0.9217 | 1.6694 | |
| HCC1569 | HER2amp | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 2 | uM | 7824.017 | 0.8223 | 0.7788 | 1.6694 |