Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| T47D | HR+ | Luminal | CGC-11047 | Polyamine analogue | 40 | uM | 9897.034 | 0.7236 | -0.1200 | 0.3940 | ||
| T47D | HR+ | Luminal | CGC-11047 | Polyamine analogue | 200 | uM | 9897.034 | 0.7245 | -0.1173 | 0.3940 | ||
| T47D | HR+ | Luminal | CGC-11047 | Polyamine analogue | 1000 | uM | 9897.034 | 0.4880 | -0.6762 | 0.3940 | ||
| T47D | HR+ | Luminal | CGC-11047 | Polyamine analogue | 5000 | uM | 9897.034 | 0.0915 | -0.9954 | 0.3940 | ||
| UACC-812 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 0.0128 | uM | 7926.018 | 1.0060 | 1.0114 | 1.0502 | ||
| UACC-812 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 0.064 | uM | 7926.018 | 1.0009 | 1.0018 | 1.0502 | ||
| UACC-812 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 0.32 | uM | 7926.018 | 1.0126 | 1.0239 | 1.0502 | ||
| UACC-812 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 1.6 | uM | 7926.018 | 0.8578 | 0.7283 | 1.0502 | ||
| UACC-812 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 8 | uM | 7926.018 | 0.8267 | 0.6685 | 1.0502 | ||
| UACC-812 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 40 | uM | 7926.018 | 0.7856 | 0.5894 | 1.0502 | ||
| UACC-812 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 200 | uM | 7926.018 | 0.7840 | 0.5864 | 1.0502 | ||
| UACC-812 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 1000 | uM | 7926.018 | 0.6848 | 0.3946 | 1.0502 | ||
| UACC-812 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 5000 | uM | 7926.018 | 0.1233 | -0.7276 | 1.0502 | ||
| UACC-812 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 0.0128 | uM | 10150.034 | 0.9691 | 0.8328 | 0.3592 | ||
| UACC-812 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 0.064 | uM | 10150.034 | 1.0279 | 1.1592 | 0.3592 | ||
| UACC-812 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 0.32 | uM | 10150.034 | 1.0977 | 1.5926 | 0.3592 | ||
| UACC-812 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 1.6 | uM | 10150.034 | 0.8727 | 0.3688 | 0.3592 | ||
| UACC-812 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 8 | uM | 10150.034 | 0.8894 | 0.4431 | 0.3592 | ||
| UACC-812 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 40 | uM | 10150.034 | 0.8521 | 0.2810 | 0.3592 | ||
| UACC-812 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 200 | uM | 10150.034 | 0.8933 | 0.4609 | 0.3592 | ||
| UACC-812 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 1000 | uM | 10150.034 | 0.7018 | -0.2536 | 0.3592 | ||
| UACC-812 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 5000 | uM | 10150.034 | 0.0282 | -0.9999 | 0.3592 | ||
| UACC-812 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 0.0128 | uM | 10151.034 | 1.0157 | 1.0987 | 0.3226 | ||
| UACC-812 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 0.064 | uM | 10151.034 | 0.9110 | 0.4980 | 0.3226 | ||
| UACC-812 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 0.32 | uM | 10151.034 | 1.0828 | 1.5593 | 0.3226 |