Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 600MPE | HR+ | Luminal | CGC-11047 | Polyamine analogue | 8 | uM | 9120.034 | 0.8734 | 0.5949 | 0.5982 | ||
| 600MPE | HR+ | Luminal | CGC-11047 | Polyamine analogue | 40 | uM | 9120.034 | 0.8755 | 0.6013 | 0.5982 | ||
| 600MPE | HR+ | Luminal | CGC-11047 | Polyamine analogue | 200 | uM | 9120.034 | 0.9295 | 0.7699 | 0.5982 | ||
| 600MPE | HR+ | Luminal | CGC-11047 | Polyamine analogue | 1000 | uM | 9120.034 | 0.8164 | 0.4248 | 0.5982 | ||
| 600MPE | HR+ | Luminal | CGC-11047 | Polyamine analogue | 5000 | uM | 9120.034 | 0.0316 | -0.9938 | 0.5982 | ||
| AU565 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 0.0128 | uM | 7793.018 | 1.0256 | 1.0387 | 1.3186 | ||
| AU565 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 0.064 | uM | 7793.018 | 0.9452 | 0.9163 | 1.3186 | ||
| AU565 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 0.32 | uM | 7793.018 | 0.8172 | 0.7161 | 1.3186 | ||
| AU565 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 1.6 | uM | 7793.018 | 0.7515 | 0.6105 | 1.3186 | ||
| AU565 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 8 | uM | 7793.018 | 0.8217 | 0.7232 | 1.3186 | ||
| AU565 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 40 | uM | 7793.018 | 0.7925 | 0.6767 | 1.3186 | ||
| AU565 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 200 | uM | 7793.018 | 0.7966 | 0.6833 | 1.3186 | ||
| AU565 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 1000 | uM | 7793.018 | 0.0475 | -0.8015 | 1.3186 | ||
| AU565 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 5000 | uM | 7793.018 | 0.0156 | -0.9147 | 1.3186 | ||
| AU565 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 0.0128 | uM | 7794.018 | 1.5159 | 1.5615 | 1.6812 | ||
| AU565 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 0.064 | uM | 7794.018 | 1.3599 | 1.4013 | 1.6812 | ||
| AU565 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 0.32 | uM | 7794.018 | 1.1516 | 1.1752 | 1.6812 | ||
| AU565 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 1.6 | uM | 7794.018 | 1.0164 | 1.0195 | 1.6812 | ||
| AU565 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 8 | uM | 7794.018 | 1.0781 | 1.0915 | 1.6812 | ||
| AU565 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 40 | uM | 7794.018 | 1.0112 | 1.0133 | 1.6812 | ||
| AU565 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 200 | uM | 7794.018 | 1.0095 | 1.0113 | 1.6812 | ||
| AU565 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 1000 | uM | 7794.018 | 0.8864 | 0.8615 | 1.6812 | ||
| AU565 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 5000 | uM | 7794.018 | 0.0686 | -0.5938 | 1.6812 | ||
| AU565 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 0.0128 | uM | 9035.018 | 1.0068 | 1.0063 | 2.1555 | ||
| AU565 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 0.064 | uM | 9035.018 | 0.9787 | 0.9801 | 2.1555 |