Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM149PT | TNBC | Basal B | Cetuximab | EGFR | ErbB | 0.0011 | uM | 7917.018 | 0.8228 | 0.8680 | 2.8573 | |
| SUM149PT | TNBC | Basal B | Cetuximab | EGFR | ErbB | 0.00548 | uM | 7917.018 | 0.7941 | 0.8450 | 2.8573 | |
| SUM149PT | TNBC | Basal B | Cetuximab | EGFR | ErbB | 0.0274 | uM | 7917.018 | 0.7651 | 0.8211 | 2.8573 | |
| SUM149PT | TNBC | Basal B | Cetuximab | EGFR | ErbB | 0.137 | uM | 7917.018 | 0.6779 | 0.7456 | 2.8573 | |
| SUM149PT | TNBC | Basal B | Cetuximab | EGFR | ErbB | 0.685 | uM | 7917.018 | 0.6623 | 0.7314 | 2.8573 | |
| SUM149PT | TNBC | Basal B | Cetuximab | EGFR | ErbB | 0.00000175 | uM | 9830.006 | 0.9918 | 0.9904 | 1.7160 | |
| SUM149PT | TNBC | Basal B | Cetuximab | EGFR | ErbB | 0.00000877 | uM | 9830.006 | 0.7918 | 0.7456 | 1.7160 | |
| SUM149PT | TNBC | Basal B | Cetuximab | EGFR | ErbB | 0.0000438 | uM | 9830.006 | 0.9735 | 0.9689 | 1.7160 | |
| SUM149PT | TNBC | Basal B | Cetuximab | EGFR | ErbB | 0.000219 | uM | 9830.006 | 1.0900 | 1.1030 | 1.7160 | |
| SUM149PT | TNBC | Basal B | Cetuximab | EGFR | ErbB | 0.0011 | uM | 9830.006 | 0.8920 | 0.8711 | 1.7160 | |
| SUM149PT | TNBC | Basal B | Cetuximab | EGFR | ErbB | 0.00548 | uM | 9830.006 | 0.7431 | 0.6822 | 1.7160 | |
| SUM149PT | TNBC | Basal B | Cetuximab | EGFR | ErbB | 0.0274 | uM | 9830.006 | 0.6825 | 0.6008 | 1.7160 | |
| SUM149PT | TNBC | Basal B | Cetuximab | EGFR | ErbB | 0.137 | uM | 9830.006 | 0.6131 | 0.5039 | 1.7160 | |
| SUM149PT | TNBC | Basal B | Cetuximab | EGFR | ErbB | 0.685 | uM | 9830.006 | 0.6108 | 0.5005 | 1.7160 | |
| SUM159PT | TNBC | Basal B | Cetuximab | EGFR | ErbB | 0.00000175 | uM | 7918.018 | 0.9658 | 0.9771 | 3.0213 | |
| SUM159PT | TNBC | Basal B | Cetuximab | EGFR | ErbB | 0.00000877 | uM | 7918.018 | 0.8117 | 0.8665 | 3.0213 | |
| SUM159PT | TNBC | Basal B | Cetuximab | EGFR | ErbB | 0.0000438 | uM | 7918.018 | 1.0466 | 1.0303 | 3.0213 | |
| SUM159PT | TNBC | Basal B | Cetuximab | EGFR | ErbB | 0.000219 | uM | 7918.018 | 0.9688 | 0.9792 | 3.0213 | |
| SUM159PT | TNBC | Basal B | Cetuximab | EGFR | ErbB | 0.0011 | uM | 7918.018 | 1.0931 | 1.0598 | 3.0213 | |
| SUM159PT | TNBC | Basal B | Cetuximab | EGFR | ErbB | 0.00548 | uM | 7918.018 | 1.0903 | 1.0580 | 3.0213 | |
| SUM159PT | TNBC | Basal B | Cetuximab | EGFR | ErbB | 0.0274 | uM | 7918.018 | 0.6849 | 0.7646 | 3.0213 | |
| SUM159PT | TNBC | Basal B | Cetuximab | EGFR | ErbB | 0.137 | uM | 7918.018 | 1.1246 | 1.0793 | 3.0213 | |
| SUM159PT | TNBC | Basal B | Cetuximab | EGFR | ErbB | 0.685 | uM | 7918.018 | 0.8949 | 0.9278 | 3.0213 | |
| SUM159PT | TNBC | Basal B | Cetuximab | EGFR | ErbB | 0.00000175 | uM | 7919.042 | 1.0002 | 1.0001 | 3.7203 | |
| SUM159PT | TNBC | Basal B | Cetuximab | EGFR | ErbB | 0.00000877 | uM | 7919.042 | 0.9825 | 0.9905 | 3.7203 |