Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset - HMS LINCS Database

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)

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Small molecules	Cells	Antibodies

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Cell	Clinical Subtype	Transcriptional Subtype	Antibody	Perturbagen Target	Perturbagen Class	Perturbagen Concentration	Perturbagen Conc Unit	Biological Replicate ID	Relative Cell Count	Normalized Growth Rate Inhibition Value	Nominal Division Rate
MDA-MB-175-VII	HR+	Luminal	Cetuximab	EGFR	ErbB	0.0274	uM	7884.018	1.0249	1.0825	0.6074
MDA-MB-175-VII	HR+	Luminal	Cetuximab	EGFR	ErbB	0.137	uM	7884.018	1.0524	1.1753	0.6074
MDA-MB-175-VII	HR+	Luminal	Cetuximab	EGFR	ErbB	0.685	uM	7884.018	1.0516	1.1727	0.6074
MDA-MB-175-VII	HR+	Luminal	Cetuximab	EGFR	ErbB	0.00000175	uM	7885.042	1.0143	1.0486	0.5912
MDA-MB-175-VII	HR+	Luminal	Cetuximab	EGFR	ErbB	0.00000877	uM	7885.042	1.0031	1.0105	0.5912
MDA-MB-175-VII	HR+	Luminal	Cetuximab	EGFR	ErbB	0.0000438	uM	7885.042	0.9571	0.8571	0.5912
MDA-MB-175-VII	HR+	Luminal	Cetuximab	EGFR	ErbB	0.000219	uM	7885.042	1.0096	1.0327	0.5912
MDA-MB-175-VII	HR+	Luminal	Cetuximab	EGFR	ErbB	0.0011	uM	7885.042	0.9817	0.9384	0.5912
MDA-MB-175-VII	HR+	Luminal	Cetuximab	EGFR	ErbB	0.00548	uM	7885.042	0.9866	0.9547	0.5912
MDA-MB-175-VII	HR+	Luminal	Cetuximab	EGFR	ErbB	0.0274	uM	7885.042	0.9759	0.9192	0.5912
MDA-MB-175-VII	HR+	Luminal	Cetuximab	EGFR	ErbB	0.137	uM	7885.042	1.0305	1.1041	0.5912
MDA-MB-175-VII	HR+	Luminal	Cetuximab	EGFR	ErbB	0.685	uM	7885.042	1.0011	1.0037	0.5912
MDA-MB-175-VII	HR+	Luminal	Cetuximab	EGFR	ErbB	0.00000175	uM	7886.042	1.0266	1.0828	0.6462
MDA-MB-175-VII	HR+	Luminal	Cetuximab	EGFR	ErbB	0.00000877	uM	7886.042	1.1042	1.3315	0.6462
MDA-MB-175-VII	HR+	Luminal	Cetuximab	EGFR	ErbB	0.0000438	uM	7886.042	1.0164	1.0511	0.6462
MDA-MB-175-VII	HR+	Luminal	Cetuximab	EGFR	ErbB	0.000219	uM	7886.042	1.0000	1.0000	0.6462
MDA-MB-175-VII	HR+	Luminal	Cetuximab	EGFR	ErbB	0.0011	uM	7886.042	1.0226	1.0704	0.6462
MDA-MB-175-VII	HR+	Luminal	Cetuximab	EGFR	ErbB	0.00548	uM	7886.042	1.0713	1.2250	0.6462
MDA-MB-175-VII	HR+	Luminal	Cetuximab	EGFR	ErbB	0.0274	uM	7886.042	0.9696	0.9065	0.6462
MDA-MB-175-VII	HR+	Luminal	Cetuximab	EGFR	ErbB	0.137	uM	7886.042	0.9847	0.9528	0.6462
MDA-MB-175-VII	HR+	Luminal	Cetuximab	EGFR	ErbB	0.685	uM	7886.042	0.9896	0.9678	0.6462
MDA-MB-231	TNBC	Basal B	Cetuximab	EGFR	ErbB	0.00000175	uM	7892.018	0.9603	0.9678	2.4903
MDA-MB-231	TNBC	Basal B	Cetuximab	EGFR	ErbB	0.00000877	uM	7892.018	0.9890	0.9911	2.4903
MDA-MB-231	TNBC	Basal B	Cetuximab	EGFR	ErbB	0.0000438	uM	7892.018	0.9808	0.9845	2.4903
MDA-MB-231	TNBC	Basal B	Cetuximab	EGFR	ErbB	0.000219	uM	7892.018	1.0041	1.0033	2.4903

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HMS LINCS Project

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)