Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF12A | NM | Basal B | Cetuximab | EGFR | ErbB | 0.000219 | uM | 10061.123 | 1.0183 | 1.0191 | 1.9064 | |
| MCF12A | NM | Basal B | Cetuximab | EGFR | ErbB | 0.0011 | uM | 10061.123 | 1.0047 | 1.0049 | 1.9064 | |
| MCF12A | NM | Basal B | Cetuximab | EGFR | ErbB | 0.00548 | uM | 10061.123 | 0.9848 | 0.9840 | 1.9064 | |
| MCF12A | NM | Basal B | Cetuximab | EGFR | ErbB | 0.0274 | uM | 10061.123 | 0.9711 | 0.9695 | 1.9064 | |
| MCF12A | NM | Basal B | Cetuximab | EGFR | ErbB | 0.137 | uM | 10061.123 | 0.9536 | 0.9508 | 1.9064 | |
| MCF12A | NM | Basal B | Cetuximab | EGFR | ErbB | 0.685 | uM | 10061.123 | 0.7010 | 0.6599 | 1.9064 | |
| MCF7 | HR+ | Luminal | Cetuximab | EGFR | ErbB | 0.00000175 | uM | 7874.018 | 1.0547 | 1.0656 | 1.6506 | |
| MCF7 | HR+ | Luminal | Cetuximab | EGFR | ErbB | 0.00000877 | uM | 7874.018 | 1.0242 | 1.0292 | 1.6506 | |
| MCF7 | HR+ | Luminal | Cetuximab | EGFR | ErbB | 0.0000438 | uM | 7874.018 | 0.9382 | 0.9241 | 1.6506 | |
| MCF7 | HR+ | Luminal | Cetuximab | EGFR | ErbB | 0.000219 | uM | 7874.018 | 1.0986 | 1.1172 | 1.6506 | |
| MCF7 | HR+ | Luminal | Cetuximab | EGFR | ErbB | 0.0011 | uM | 7874.018 | 1.0748 | 1.0893 | 1.6506 | |
| MCF7 | HR+ | Luminal | Cetuximab | EGFR | ErbB | 0.00548 | uM | 7874.018 | 1.0532 | 1.0638 | 1.6506 | |
| MCF7 | HR+ | Luminal | Cetuximab | EGFR | ErbB | 0.0274 | uM | 7874.018 | 1.0629 | 1.0753 | 1.6506 | |
| MCF7 | HR+ | Luminal | Cetuximab | EGFR | ErbB | 0.137 | uM | 7874.018 | 1.0427 | 1.0513 | 1.6506 | |
| MCF7 | HR+ | Luminal | Cetuximab | EGFR | ErbB | 0.685 | uM | 7874.018 | 0.9681 | 0.9611 | 1.6506 | |
| MCF7 | HR+ | Luminal | Cetuximab | EGFR | ErbB | 0.00000175 | uM | 7875.018 | 0.9881 | 0.9856 | 1.6565 | |
| MCF7 | HR+ | Luminal | Cetuximab | EGFR | ErbB | 0.00000877 | uM | 7875.018 | 1.0225 | 1.0271 | 1.6565 | |
| MCF7 | HR+ | Luminal | Cetuximab | EGFR | ErbB | 0.0000438 | uM | 7875.018 | 0.9967 | 0.9960 | 1.6565 | |
| MCF7 | HR+ | Luminal | Cetuximab | EGFR | ErbB | 0.000219 | uM | 7875.018 | 1.0314 | 1.0377 | 1.6565 | |
| MCF7 | HR+ | Luminal | Cetuximab | EGFR | ErbB | 0.0011 | uM | 7875.018 | 1.0107 | 1.0129 | 1.6565 | |
| MCF7 | HR+ | Luminal | Cetuximab | EGFR | ErbB | 0.00548 | uM | 7875.018 | 1.0415 | 1.0497 | 1.6565 | |
| MCF7 | HR+ | Luminal | Cetuximab | EGFR | ErbB | 0.0274 | uM | 7875.018 | 1.0330 | 1.0395 | 1.6565 | |
| MCF7 | HR+ | Luminal | Cetuximab | EGFR | ErbB | 0.137 | uM | 7875.018 | 0.9898 | 0.9877 | 1.6565 | |
| MCF7 | HR+ | Luminal | Cetuximab | EGFR | ErbB | 0.685 | uM | 7875.018 | 0.9440 | 0.9316 | 1.6565 | |
| MCF7 | HR+ | Luminal | Cetuximab | EGFR | ErbB | 0.00000175 | uM | 9583.026 | 0.9952 | 0.9924 | 1.2731 |