Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
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MCF 10F | NM | - | Cetuximab | EGFR | ErbB | 0.00548 | uM | 9566.026 | 1.0244 | 1.0227 | 2.1367 | |
MCF 10F | NM | - | Cetuximab | EGFR | ErbB | 0.0274 | uM | 9566.026 | 0.9912 | 0.9917 | 2.1367 | |
MCF 10F | NM | - | Cetuximab | EGFR | ErbB | 0.137 | uM | 9566.026 | 1.0340 | 1.0316 | 2.1367 | |
MCF 10F | NM | - | Cetuximab | EGFR | ErbB | 0.685 | uM | 9566.026 | 0.8637 | 0.8674 | 2.1367 | |
MCF12A | NM | Basal B | Cetuximab | EGFR | ErbB | 0.00000175 | uM | 7489.102 | 1.0096 | 1.0079 | 2.4234 | |
MCF12A | NM | Basal B | Cetuximab | EGFR | ErbB | 0.00000877 | uM | 7489.102 | 1.0087 | 1.0071 | 2.4234 | |
MCF12A | NM | Basal B | Cetuximab | EGFR | ErbB | 0.0000438 | uM | 7489.102 | 0.9911 | 0.9926 | 2.4234 | |
MCF12A | NM | Basal B | Cetuximab | EGFR | ErbB | 0.000219 | uM | 7489.102 | 1.0072 | 1.0059 | 2.4234 | |
MCF12A | NM | Basal B | Cetuximab | EGFR | ErbB | 0.0011 | uM | 7489.102 | 0.9676 | 0.9730 | 2.4234 | |
MCF12A | NM | Basal B | Cetuximab | EGFR | ErbB | 0.00548 | uM | 7489.102 | 0.9293 | 0.9404 | 2.4234 | |
MCF12A | NM | Basal B | Cetuximab | EGFR | ErbB | 0.0274 | uM | 7489.102 | 0.8336 | 0.8553 | 2.4234 | |
MCF12A | NM | Basal B | Cetuximab | EGFR | ErbB | 0.137 | uM | 7489.102 | 0.7686 | 0.7942 | 2.4234 | |
MCF12A | NM | Basal B | Cetuximab | EGFR | ErbB | 0.685 | uM | 7489.102 | 0.5997 | 0.6195 | 2.4234 | |
MCF12A | NM | Basal B | Cetuximab | EGFR | ErbB | 0.00000175 | uM | 7873.042 | 0.9898 | 0.9906 | 2.1928 | |
MCF12A | NM | Basal B | Cetuximab | EGFR | ErbB | 0.00000877 | uM | 7873.042 | 1.0295 | 1.0266 | 2.1928 | |
MCF12A | NM | Basal B | Cetuximab | EGFR | ErbB | 0.0000438 | uM | 7873.042 | 0.9911 | 0.9919 | 2.1928 | |
MCF12A | NM | Basal B | Cetuximab | EGFR | ErbB | 0.000219 | uM | 7873.042 | 1.0233 | 1.0211 | 2.1928 | |
MCF12A | NM | Basal B | Cetuximab | EGFR | ErbB | 0.0011 | uM | 7873.042 | 1.0200 | 1.0182 | 2.1928 | |
MCF12A | NM | Basal B | Cetuximab | EGFR | ErbB | 0.00548 | uM | 7873.042 | 1.0017 | 1.0016 | 2.1928 | |
MCF12A | NM | Basal B | Cetuximab | EGFR | ErbB | 0.0274 | uM | 7873.042 | 0.9664 | 0.9691 | 2.1928 | |
MCF12A | NM | Basal B | Cetuximab | EGFR | ErbB | 0.137 | uM | 7873.042 | 0.9094 | 0.9152 | 2.1928 | |
MCF12A | NM | Basal B | Cetuximab | EGFR | ErbB | 0.685 | uM | 7873.042 | 0.7175 | 0.7190 | 2.1928 | |
MCF12A | NM | Basal B | Cetuximab | EGFR | ErbB | 0.00000175 | uM | 10061.123 | 1.0778 | 1.0801 | 1.9064 | |
MCF12A | NM | Basal B | Cetuximab | EGFR | ErbB | 0.00000877 | uM | 10061.123 | 0.9962 | 0.9960 | 1.9064 | |
MCF12A | NM | Basal B | Cetuximab | EGFR | ErbB | 0.0000438 | uM | 10061.123 | 1.0239 | 1.0249 | 1.9064 |