Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
---|---|---|---|---|---|---|---|---|---|---|---|---|
LY2 | HR+ | Luminal | Cetuximab | EGFR | ErbB | 0.0000438 | uM | 10264.026 | 0.9775 | 0.9700 | 1.5047 | |
LY2 | HR+ | Luminal | Cetuximab | EGFR | ErbB | 0.000219 | uM | 10264.026 | 0.9825 | 0.9766 | 1.5047 | |
LY2 | HR+ | Luminal | Cetuximab | EGFR | ErbB | 0.0011 | uM | 10264.026 | 0.9930 | 0.9907 | 1.5047 | |
LY2 | HR+ | Luminal | Cetuximab | EGFR | ErbB | 0.00548 | uM | 10264.026 | 1.0213 | 1.0282 | 1.5047 | |
LY2 | HR+ | Luminal | Cetuximab | EGFR | ErbB | 0.0274 | uM | 10264.026 | 0.9966 | 0.9955 | 1.5047 | |
LY2 | HR+ | Luminal | Cetuximab | EGFR | ErbB | 0.137 | uM | 10264.026 | 1.0224 | 1.0297 | 1.5047 | |
LY2 | HR+ | Luminal | Cetuximab | EGFR | ErbB | 0.685 | uM | 10264.026 | 0.9779 | 0.9706 | 1.5047 | |
MCF 10A | NM | Basal B | Cetuximab | EGFR | ErbB | 0.00000175 | uM | 7867.042 | 1.0737 | 1.0616 | 2.3427 | |
MCF 10A | NM | Basal B | Cetuximab | EGFR | ErbB | 0.00000877 | uM | 7867.042 | 1.1028 | 1.0853 | 2.3427 | |
MCF 10A | NM | Basal B | Cetuximab | EGFR | ErbB | 0.0000438 | uM | 7867.042 | 1.0077 | 1.0066 | 2.3427 | |
MCF 10A | NM | Basal B | Cetuximab | EGFR | ErbB | 0.000219 | uM | 7867.042 | 0.9754 | 0.9789 | 2.3427 | |
MCF 10A | NM | Basal B | Cetuximab | EGFR | ErbB | 0.0011 | uM | 7867.042 | 1.0591 | 1.0497 | 2.3427 | |
MCF 10A | NM | Basal B | Cetuximab | EGFR | ErbB | 0.00548 | uM | 7867.042 | 1.0426 | 1.0359 | 2.3427 | |
MCF 10A | NM | Basal B | Cetuximab | EGFR | ErbB | 0.0274 | uM | 7867.042 | 0.9230 | 0.9328 | 2.3427 | |
MCF 10A | NM | Basal B | Cetuximab | EGFR | ErbB | 0.137 | uM | 7867.042 | 0.7745 | 0.7933 | 2.3427 | |
MCF 10A | NM | Basal B | Cetuximab | EGFR | ErbB | 0.685 | uM | 7867.042 | 0.5266 | 0.5210 | 2.3427 | |
MCF 10A | NM | Basal B | Cetuximab | EGFR | ErbB | 0.00000175 | uM | 7868.018 | 1.0334 | 1.0314 | 2.1110 | |
MCF 10A | NM | Basal B | Cetuximab | EGFR | ErbB | 0.00000877 | uM | 7868.018 | 1.0757 | 1.0704 | 2.1110 | |
MCF 10A | NM | Basal B | Cetuximab | EGFR | ErbB | 0.0000438 | uM | 7868.018 | 1.0004 | 1.0004 | 2.1110 | |
MCF 10A | NM | Basal B | Cetuximab | EGFR | ErbB | 0.000219 | uM | 7868.018 | 1.0800 | 1.0743 | 2.1110 | |
MCF 10A | NM | Basal B | Cetuximab | EGFR | ErbB | 0.0011 | uM | 7868.018 | 0.9951 | 0.9953 | 2.1110 | |
MCF 10A | NM | Basal B | Cetuximab | EGFR | ErbB | 0.00548 | uM | 7868.018 | 0.9631 | 0.9647 | 2.1110 | |
MCF 10A | NM | Basal B | Cetuximab | EGFR | ErbB | 0.0274 | uM | 7868.018 | 1.0459 | 1.0429 | 2.1110 | |
MCF 10A | NM | Basal B | Cetuximab | EGFR | ErbB | 0.137 | uM | 7868.018 | 0.9738 | 0.9750 | 2.1110 | |
MCF 10A | NM | Basal B | Cetuximab | EGFR | ErbB | 0.685 | uM | 7868.018 | 0.9173 | 0.9199 | 2.1110 |