Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1806 | TNBC | Basal A | Cetuximab | EGFR | ErbB | 0.0011 | uM | 9376.026 | 0.9271 | 0.9120 | 1.6827 | |
| HCC1806 | TNBC | Basal A | Cetuximab | EGFR | ErbB | 0.00548 | uM | 9376.026 | 0.8422 | 0.8059 | 1.6827 | |
| HCC1806 | TNBC | Basal A | Cetuximab | EGFR | ErbB | 0.0274 | uM | 9376.026 | 0.7958 | 0.7461 | 1.6827 | |
| HCC1806 | TNBC | Basal A | Cetuximab | EGFR | ErbB | 0.137 | uM | 9376.026 | 0.7997 | 0.7512 | 1.6827 | |
| HCC1806 | TNBC | Basal A | Cetuximab | EGFR | ErbB | 0.685 | uM | 9376.026 | 0.7148 | 0.6382 | 1.6827 | |
| HCC1937 | TNBC | Basal A | Cetuximab | EGFR | ErbB | 0.00000175 | uM | 7832.042 | 1.0048 | 1.0075 | 1.2810 | |
| HCC1937 | TNBC | Basal A | Cetuximab | EGFR | ErbB | 0.00000877 | uM | 7832.042 | 0.9931 | 0.9892 | 1.2810 | |
| HCC1937 | TNBC | Basal A | Cetuximab | EGFR | ErbB | 0.0000438 | uM | 7832.042 | 1.0460 | 1.0715 | 1.2810 | |
| HCC1937 | TNBC | Basal A | Cetuximab | EGFR | ErbB | 0.000219 | uM | 7832.042 | 1.0371 | 1.0578 | 1.2810 | |
| HCC1937 | TNBC | Basal A | Cetuximab | EGFR | ErbB | 0.0011 | uM | 7832.042 | 0.9158 | 0.8673 | 1.2810 | |
| HCC1937 | TNBC | Basal A | Cetuximab | EGFR | ErbB | 0.00548 | uM | 7832.042 | 0.9131 | 0.8629 | 1.2810 | |
| HCC1937 | TNBC | Basal A | Cetuximab | EGFR | ErbB | 0.0274 | uM | 7832.042 | 0.9862 | 0.9784 | 1.2810 | |
| HCC1937 | TNBC | Basal A | Cetuximab | EGFR | ErbB | 0.137 | uM | 7832.042 | 0.9111 | 0.8598 | 1.2810 | |
| HCC1937 | TNBC | Basal A | Cetuximab | EGFR | ErbB | 0.685 | uM | 7832.042 | 0.6520 | 0.4323 | 1.2810 | |
| HCC1937 | TNBC | Basal A | Cetuximab | EGFR | ErbB | 0.00000175 | uM | 7833.042 | 0.9237 | 0.8521 | 1.0332 | |
| HCC1937 | TNBC | Basal A | Cetuximab | EGFR | ErbB | 0.00000877 | uM | 7833.042 | 0.9736 | 0.9489 | 1.0332 | |
| HCC1937 | TNBC | Basal A | Cetuximab | EGFR | ErbB | 0.0000438 | uM | 7833.042 | 0.9602 | 0.9229 | 1.0332 | |
| HCC1937 | TNBC | Basal A | Cetuximab | EGFR | ErbB | 0.000219 | uM | 7833.042 | 0.9750 | 0.9516 | 1.0332 | |
| HCC1937 | TNBC | Basal A | Cetuximab | EGFR | ErbB | 0.0011 | uM | 7833.042 | 0.9857 | 0.9722 | 1.0332 | |
| HCC1937 | TNBC | Basal A | Cetuximab | EGFR | ErbB | 0.00548 | uM | 7833.042 | 0.8972 | 0.8006 | 1.0332 | |
| HCC1937 | TNBC | Basal A | Cetuximab | EGFR | ErbB | 0.0274 | uM | 7833.042 | 0.9263 | 0.8572 | 1.0332 | |
| HCC1937 | TNBC | Basal A | Cetuximab | EGFR | ErbB | 0.137 | uM | 7833.042 | 0.9409 | 0.8856 | 1.0332 | |
| HCC1937 | TNBC | Basal A | Cetuximab | EGFR | ErbB | 0.685 | uM | 7833.042 | 0.9560 | 0.9148 | 1.0332 | |
| HCC1937 | TNBC | Basal A | Cetuximab | EGFR | ErbB | 0.00000175 | uM | 7834.018 | 1.0667 | 1.0693 | 1.8951 | |
| HCC1937 | TNBC | Basal A | Cetuximab | EGFR | ErbB | 0.00000877 | uM | 7834.018 | 0.9406 | 0.9364 | 1.8951 |