Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC2185 | TNBC | Luminal | Bortezomib | Proteasome | Proteasome | 33.3 | uM | 7463.074 | 0.2685 | -0.8872 | 0.4574 | |
| HCC2185 | TNBC | Luminal | Bortezomib | Proteasome | Proteasome | 33.3 | uM | 7463.074 | 0.2685 | -0.8872 | 0.4574 | |
| HCC2185 | TNBC | Luminal | Bortezomib | Proteasome | Proteasome | 167 | uM | 7463.074 | 0.2166 | -0.9295 | 0.4574 | |
| HCC2185 | TNBC | Luminal | Bortezomib | Proteasome | Proteasome | 167 | uM | 7463.074 | 0.2166 | -0.9295 | 0.4574 | |
| HCC2185 | TNBC | Luminal | Bortezomib | Proteasome | Proteasome | 0.000427 | uM | 7464.074 | 1.0684 | 1.2556 | 0.5504 | |
| HCC2185 | TNBC | Luminal | Bortezomib | Proteasome | Proteasome | 0.000427 | uM | 7464.074 | 1.0684 | 1.2556 | 0.5504 | |
| HCC2185 | TNBC | Luminal | Bortezomib | Proteasome | Proteasome | 0.00213 | uM | 7464.074 | 1.0424 | 1.1566 | 0.5504 | |
| HCC2185 | TNBC | Luminal | Bortezomib | Proteasome | Proteasome | 0.00213 | uM | 7464.074 | 1.0424 | 1.1566 | 0.5504 | |
| HCC2185 | TNBC | Luminal | Bortezomib | Proteasome | Proteasome | 0.0107 | uM | 7464.074 | 1.0131 | 1.0479 | 0.5504 | |
| HCC2185 | TNBC | Luminal | Bortezomib | Proteasome | Proteasome | 0.0107 | uM | 7464.074 | 1.0131 | 1.0479 | 0.5504 | |
| HCC2185 | TNBC | Luminal | Bortezomib | Proteasome | Proteasome | 0.0533 | uM | 7464.074 | 0.6088 | -0.1882 | 0.5504 | |
| HCC2185 | TNBC | Luminal | Bortezomib | Proteasome | Proteasome | 0.0533 | uM | 7464.074 | 0.6088 | -0.1882 | 0.5504 | |
| HCC2185 | TNBC | Luminal | Bortezomib | Proteasome | Proteasome | 0.267 | uM | 7464.074 | 0.2878 | -0.7919 | 0.5504 | |
| HCC2185 | TNBC | Luminal | Bortezomib | Proteasome | Proteasome | 0.267 | uM | 7464.074 | 0.2878 | -0.7919 | 0.5504 | |
| HCC2185 | TNBC | Luminal | Bortezomib | Proteasome | Proteasome | 1.33 | uM | 7464.074 | 0.3057 | -0.7678 | 0.5504 | |
| HCC2185 | TNBC | Luminal | Bortezomib | Proteasome | Proteasome | 1.33 | uM | 7464.074 | 0.3057 | -0.7678 | 0.5504 | |
| HCC2185 | TNBC | Luminal | Bortezomib | Proteasome | Proteasome | 6.67 | uM | 7464.074 | 0.1916 | -0.9007 | 0.5504 | |
| HCC2185 | TNBC | Luminal | Bortezomib | Proteasome | Proteasome | 6.67 | uM | 7464.074 | 0.1916 | -0.9007 | 0.5504 | |
| HCC2185 | TNBC | Luminal | Bortezomib | Proteasome | Proteasome | 33.3 | uM | 7464.074 | 0.1575 | -0.9304 | 0.5504 | |
| HCC2185 | TNBC | Luminal | Bortezomib | Proteasome | Proteasome | 33.3 | uM | 7464.074 | 0.1575 | -0.9304 | 0.5504 | |
| HCC2185 | TNBC | Luminal | Bortezomib | Proteasome | Proteasome | 167 | uM | 7464.074 | 0.1572 | -0.9307 | 0.5504 | |
| HCC2185 | TNBC | Luminal | Bortezomib | Proteasome | Proteasome | 167 | uM | 7464.074 | 0.1572 | -0.9307 | 0.5504 | |
| HCC3153 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.000427 | uM | 7466.074 | 1.0339 | 1.0698 | 0.9724 | |
| HCC3153 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.000427 | uM | 7466.074 | 1.0339 | 1.0698 | 0.9724 | |
| HCC3153 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.00213 | uM | 7466.074 | 0.9792 | 0.9573 | 0.9724 |