Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-436 | TNBC | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 167 | uM | 7898.016 | 0.0142 | -0.9401 | 1.2127 | ||
| MDA-MB-436 | TNBC | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 0.000427 | uM | 7902.016 | 1.1359 | 1.1387 | 1.9004 | ||
| MDA-MB-436 | TNBC | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 0.00213 | uM | 7902.016 | 0.7126 | 0.6734 | 1.9004 | ||
| MDA-MB-436 | TNBC | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 0.0107 | uM | 7902.016 | 1.1721 | 1.1743 | 1.9004 | ||
| MDA-MB-436 | TNBC | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 0.0533 | uM | 7902.016 | 0.8724 | 0.8613 | 1.9004 | ||
| MDA-MB-436 | TNBC | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 0.267 | uM | 7902.016 | 1.0193 | 1.0203 | 1.9004 | ||
| MDA-MB-436 | TNBC | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 1.33 | uM | 7902.016 | 0.8269 | 0.8097 | 1.9004 | ||
| MDA-MB-436 | TNBC | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 6.67 | uM | 7902.016 | 0.8002 | 0.7786 | 1.9004 | ||
| MDA-MB-436 | TNBC | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 33.3 | uM | 7902.016 | 0.8746 | 0.8639 | 1.9004 | ||
| MDA-MB-436 | TNBC | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 167 | uM | 7902.016 | 0.5429 | 0.4502 | 1.9004 | ||
| MDA-MB-453 | TNBC | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 0.000427 | uM | 7903.016 | 1.0694 | 1.1234 | 1.1196 | ||
| MDA-MB-453 | TNBC | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 0.00213 | uM | 7903.016 | 1.0201 | 1.0358 | 1.1196 | ||
| MDA-MB-453 | TNBC | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 0.0107 | uM | 7903.016 | 0.9909 | 0.9837 | 1.1196 | ||
| MDA-MB-453 | TNBC | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 0.0533 | uM | 7903.016 | 0.9672 | 0.9414 | 1.1196 | ||
| MDA-MB-453 | TNBC | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 0.267 | uM | 7903.016 | 1.0149 | 1.0266 | 1.1196 | ||
| MDA-MB-453 | TNBC | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 1.33 | uM | 7903.016 | 1.0254 | 1.0453 | 1.1196 | ||
| MDA-MB-453 | TNBC | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 6.67 | uM | 7903.016 | 1.0389 | 1.0693 | 1.1196 | ||
| MDA-MB-453 | TNBC | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 33.3 | uM | 7903.016 | 0.0252 | -0.9253 | 1.1196 | ||
| MDA-MB-453 | TNBC | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 167 | uM | 7903.016 | 0.0122 | -0.9610 | 1.1196 | ||
| MDA-MB-453 | TNBC | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 0.000427 | uM | 9708.019 | 1.0907 | 1.1558 | 1.1580 | ||
| MDA-MB-453 | TNBC | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 0.00213 | uM | 9708.019 | 1.0559 | 1.0961 | 1.1580 | ||
| MDA-MB-453 | TNBC | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 0.0107 | uM | 9708.019 | 1.0972 | 1.1667 | 1.1580 | ||
| MDA-MB-453 | TNBC | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 0.0533 | uM | 9708.019 | 0.9783 | 0.9625 | 1.1580 | ||
| MDA-MB-453 | TNBC | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 0.267 | uM | 9708.019 | 1.0572 | 1.0984 | 1.1580 | ||
| MDA-MB-453 | TNBC | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 1.33 | uM | 9708.019 | 1.0433 | 1.0746 | 1.1580 |