Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BT-483 | HR+ | Luminal | XRP44X | ELK3 | MAPK | 0.0427 | uM | 10696.151 | 0.9422 | 0.7018 | 0.3690 | |
| BT-483 | HR+ | Luminal | XRP44X | ELK3 | MAPK | 0.213 | uM | 10696.151 | 0.9749 | 0.8668 | 0.3690 | |
| BT-483 | HR+ | Luminal | XRP44X | ELK3 | MAPK | 1.07 | uM | 10696.151 | 0.6996 | -0.2405 | 0.3690 | |
| BT-483 | HR+ | Luminal | XRP44X | ELK3 | MAPK | 5.33 | uM | 10696.151 | 0.7590 | -0.0527 | 0.3690 | |
| BT-483 | HR+ | Luminal | XRP44X | ELK3 | MAPK | 26.7 | uM | 10696.151 | 0.6095 | -0.4773 | 0.3690 | |
| BT-483 | HR+ | Luminal | XRP44X | ELK3 | MAPK | 133 | uM | 10696.151 | 0.3774 | -0.8574 | 0.3690 | |
| BT-483 | HR+ | Luminal | XRP44X | ELK3 | MAPK | 0.000341 | uM | 11855.157 | 0.9472 | 0.8687 | 0.7986 | |
| BT-483 | HR+ | Luminal | XRP44X | ELK3 | MAPK | 0.00171 | uM | 11855.157 | 0.9126 | 0.7835 | 0.7986 | |
| BT-483 | HR+ | Luminal | XRP44X | ELK3 | MAPK | 0.00853 | uM | 11855.157 | 0.9216 | 0.8056 | 0.7986 | |
| BT-483 | HR+ | Luminal | XRP44X | ELK3 | MAPK | 0.0427 | uM | 11855.157 | 0.9438 | 0.8603 | 0.7986 | |
| BT-483 | HR+ | Luminal | XRP44X | ELK3 | MAPK | 0.213 | uM | 11855.157 | 0.9046 | 0.7639 | 0.7986 | |
| BT-483 | HR+ | Luminal | XRP44X | ELK3 | MAPK | 1.07 | uM | 11855.157 | 0.8928 | 0.7352 | 0.7986 | |
| BT-483 | HR+ | Luminal | XRP44X | ELK3 | MAPK | 5.33 | uM | 11855.157 | 0.8009 | 0.5147 | 0.7986 | |
| BT-483 | HR+ | Luminal | XRP44X | ELK3 | MAPK | 26.7 | uM | 11855.157 | 0.7938 | 0.4977 | 0.7986 | |
| BT-483 | HR+ | Luminal | XRP44X | ELK3 | MAPK | 133 | uM | 11855.157 | 0.7998 | 0.5118 | 0.7986 | |
| BT-549 | TNBC | Basal B | XRP44X | ELK3 | MAPK | 0.000341 | uM | 12305.157 | 0.8912 | 0.9246 | 2.9955 | |
| BT-549 | TNBC | Basal B | XRP44X | ELK3 | MAPK | 0.00171 | uM | 12305.157 | 0.8690 | 0.9084 | 2.9955 | |
| BT-549 | TNBC | Basal B | XRP44X | ELK3 | MAPK | 0.00853 | uM | 12305.157 | 0.9453 | 0.9628 | 2.9955 | |
| BT-549 | TNBC | Basal B | XRP44X | ELK3 | MAPK | 0.0427 | uM | 12305.157 | 0.9114 | 0.9390 | 2.9955 | |
| BT-549 | TNBC | Basal B | XRP44X | ELK3 | MAPK | 0.213 | uM | 12305.157 | 0.8666 | 0.9067 | 2.9955 | |
| BT-549 | TNBC | Basal B | XRP44X | ELK3 | MAPK | 1.07 | uM | 12305.157 | 0.6821 | 0.7602 | 2.9955 | |
| BT-549 | TNBC | Basal B | XRP44X | ELK3 | MAPK | 5.33 | uM | 12305.157 | 0.2093 | 0.1864 | 2.9955 | |
| BT-549 | TNBC | Basal B | XRP44X | ELK3 | MAPK | 26.7 | uM | 12305.157 | 0.2319 | 0.2279 | 2.9955 | |
| BT-549 | TNBC | Basal B | XRP44X | ELK3 | MAPK | 133 | uM | 12305.157 | 0.4009 | 0.4741 | 2.9955 | |
| CAMA-1 | HR+ | Luminal | XRP44X | ELK3 | MAPK | 0.000341 | uM | 10473.139 | 1.0545 | 1.0900 | 1.2054 |