Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset - HMS LINCS Database

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)

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Small molecules	Cells	Antibodies

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Cell	Clinical Subtype	Transcriptional Subtype	Small Molecule	Perturbagen Target	Perturbagen Class	Perturbagen Concentration	Perturbagen Conc Unit	Biological Replicate ID	Relative Cell Count	Normalized Growth Rate Inhibition Value	Nominal Division Rate
BT-20	TNBC	Basal A	Vorinostat	HDAC	HDAC	0.048	uM	5904.065	0.9533	0.9198	1.1681
BT-20	TNBC	Basal A	Vorinostat	HDAC	HDAC	0.24	uM	5904.065	0.9611	0.9331	1.1681
BT-20	TNBC	Basal A	Vorinostat	HDAC	HDAC	1.2	uM	5904.065	0.9692	0.9472	1.1681
BT-20	TNBC	Basal A	Vorinostat	HDAC	HDAC	6	uM	5904.065	1.0144	1.0247	1.1681
BT-20	TNBC	Basal A	Vorinostat	HDAC	HDAC	30	uM	5904.065	0.8969	0.8220	1.1681
BT-20	TNBC	Basal A	Vorinostat	HDAC	HDAC	150	uM	5904.065	0.6833	0.4436	1.1681
BT-20	TNBC	Basal A	Vorinostat	HDAC	HDAC	750	uM	5904.065	0.2045	-0.4861	1.1681
BT-20	TNBC	Basal A	Vorinostat	HDAC	HDAC	3750	uM	5904.065	0.0476	-0.8523	1.1681
BT-20	TNBC	Basal A	Vorinostat	HDAC	HDAC	18700	uM	5904.065	0.0275	-0.9078	1.1681
BT-20	TNBC	Basal A	Vorinostat	HDAC	HDAC	0.048	uM	10385.065	0.7786	0.3688	0.6599
BT-20	TNBC	Basal A	Vorinostat	HDAC	HDAC	0.24	uM	10385.065	0.9041	0.7167	0.6599
BT-20	TNBC	Basal A	Vorinostat	HDAC	HDAC	1.2	uM	10385.065	0.9504	0.8517	0.6599
BT-20	TNBC	Basal A	Vorinostat	HDAC	HDAC	6	uM	10385.065	0.8282	0.5031	0.6599
BT-20	TNBC	Basal A	Vorinostat	HDAC	HDAC	30	uM	10385.065	1.1356	1.4251	0.6599
BT-20	TNBC	Basal A	Vorinostat	HDAC	HDAC	150	uM	10385.065	0.8626	0.5988	0.6599
BT-20	TNBC	Basal A	Vorinostat	HDAC	HDAC	750	uM	10385.065	0.3658	-0.5644	0.6599
BT-20	TNBC	Basal A	Vorinostat	HDAC	HDAC	3750	uM	10385.065	0.0876	-0.9500	0.6599
BT-20	TNBC	Basal A	Vorinostat	HDAC	HDAC	18700	uM	10385.065	0.0338	-0.9882	0.6599
BT-474	HER2amp	Luminal	Vorinostat	HDAC	HDAC	0.048	uM	5905.065	1.0080	1.0189	0.8461
BT-474	HER2amp	Luminal	Vorinostat	HDAC	HDAC	0.24	uM	5905.065	1.0081	1.0192	0.8461
BT-474	HER2amp	Luminal	Vorinostat	HDAC	HDAC	1.2	uM	5905.065	1.0565	1.1343	0.8461
BT-474	HER2amp	Luminal	Vorinostat	HDAC	HDAC	6	uM	5905.065	1.0169	1.0400	0.8461
BT-474	HER2amp	Luminal	Vorinostat	HDAC	HDAC	30	uM	5905.065	0.9274	0.8296	0.8461
BT-474	HER2amp	Luminal	Vorinostat	HDAC	HDAC	150	uM	5905.065	0.4673	-0.1862	0.8461
BT-474	HER2amp	Luminal	Vorinostat	HDAC	HDAC	750	uM	5905.065	0.0452	-0.9485	0.8461

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HMS LINCS Project

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)