Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC70 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 0.0148 | uM | 7856.018 | 0.2441 | -0.5547 | 0.9388 | |
| HCC70 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 0.0742 | uM | 7856.018 | 0.4404 | -0.1651 | 0.9388 | |
| HCC70 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 0.371 | uM | 7856.018 | 0.3458 | -0.3547 | 0.9388 | |
| HCC70 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 1.85 | uM | 7856.018 | 0.3296 | -0.3869 | 0.9388 | |
| HCC70 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 9.27 | uM | 7856.018 | 0.3264 | -0.3933 | 0.9388 | |
| HCC70 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 46.4 | uM | 7856.018 | 0.0108 | -0.9839 | 0.9388 | |
| HCC70 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 0.000119 | uM | 7857.042 | 0.7806 | 0.6245 | 1.1910 | |
| HCC70 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 0.000593 | uM | 7857.042 | 0.7833 | 0.6291 | 1.1910 | |
| HCC70 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 0.00297 | uM | 7857.042 | 1.0134 | 1.0226 | 1.1910 | |
| HCC70 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 0.0148 | uM | 7857.042 | 0.9603 | 0.9331 | 1.1910 | |
| HCC70 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 0.0742 | uM | 7857.042 | 0.5142 | 0.1443 | 1.1910 | |
| HCC70 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 0.371 | uM | 7857.042 | 0.2840 | -0.3049 | 1.1910 | |
| HCC70 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 1.85 | uM | 7857.042 | 0.3131 | -0.2455 | 1.1910 | |
| HCC70 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 9.27 | uM | 7857.042 | 0.3040 | -0.2641 | 1.1910 | |
| HCC70 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 46.4 | uM | 7857.042 | 0.0145 | -0.9430 | 1.1910 | |
| HCC70 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 0.000119 | uM | 7860.042 | 0.9142 | 0.7507 | 0.6736 | |
| HCC70 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 0.000593 | uM | 7860.042 | 0.9772 | 0.9327 | 0.6736 | |
| HCC70 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 0.00297 | uM | 7860.042 | 1.0376 | 1.1128 | 0.6736 | |
| HCC70 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 0.0148 | uM | 7860.042 | 0.5366 | -0.2063 | 0.6736 | |
| HCC70 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 0.0742 | uM | 7860.042 | 0.6118 | -0.0357 | 0.6736 | |
| HCC70 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 0.371 | uM | 7860.042 | 0.5703 | -0.1312 | 0.6736 | |
| HCC70 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 1.85 | uM | 7860.042 | 0.5397 | -0.1995 | 0.6736 | |
| HCC70 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 9.27 | uM | 7860.042 | 0.5455 | -0.1867 | 0.6736 | |
| HCC70 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 46.4 | uM | 7860.042 | 0.0323 | -0.9878 | 0.6736 | |
| HMT-3522 S1 | Unknown | Unknown | Vinorelbine | TUBB | TUBB | 0.000119 | uM | 7911.018 | 0.9957 | 0.9953 | 1.8543 |