Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC3153 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 0.00213 | uM | 10577.072 | 0.9677 | 0.9342 | 0.9803 | |
| HCC3153 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 0.0107 | uM | 10577.072 | 1.0110 | 1.0224 | 0.9803 | |
| HCC3153 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 0.0533 | uM | 10577.072 | 1.0061 | 1.0124 | 0.9803 | |
| HCC3153 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 0.267 | uM | 10577.072 | 0.9728 | 0.9445 | 0.9803 | |
| HCC3153 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 1.33 | uM | 10577.072 | 0.9692 | 0.9373 | 0.9803 | |
| HCC3153 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 6.67 | uM | 10577.072 | 1.0286 | 1.0584 | 0.9803 | |
| HCC3153 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 33.3 | uM | 10577.072 | 0.6274 | 0.2431 | 0.9803 | |
| HCC3153 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 167 | uM | 10577.072 | 0.4872 | -0.0395 | 0.9803 | |
| HCC3153 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 0.000427 | uM | 10937.072 | 1.0181 | 1.0276 | 1.3076 | |
| HCC3153 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 0.00213 | uM | 10937.072 | 1.0523 | 1.0796 | 1.3076 | |
| HCC3153 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 0.0107 | uM | 10937.072 | 1.0527 | 1.0801 | 1.3076 | |
| HCC3153 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 0.0533 | uM | 10937.072 | 1.0999 | 1.1511 | 1.3076 | |
| HCC3153 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 0.267 | uM | 10937.072 | 1.0287 | 1.0437 | 1.3076 | |
| HCC3153 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 1.33 | uM | 10937.072 | 1.0528 | 1.0803 | 1.3076 | |
| HCC3153 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 6.67 | uM | 10937.072 | 0.9430 | 0.9121 | 1.3076 | |
| HCC3153 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 33.3 | uM | 10937.072 | 0.5542 | 0.2735 | 1.3076 | |
| HCC3153 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 167 | uM | 10937.072 | 0.4227 | 0.0352 | 1.3076 | |
| HCC38 | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 0.000427 | uM | 7468.073 | 1.0022 | 1.0032 | 1.4124 | |
| HCC38 | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 0.00213 | uM | 7468.073 | 0.9227 | 0.8893 | 1.4124 | |
| HCC38 | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 0.0107 | uM | 7468.073 | 0.9322 | 0.9030 | 1.4124 | |
| HCC38 | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 0.0533 | uM | 7468.073 | 0.9392 | 0.9131 | 1.4124 | |
| HCC38 | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 0.267 | uM | 7468.073 | 0.9637 | 0.9483 | 1.4124 | |
| HCC38 | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 1.33 | uM | 7468.073 | 0.9078 | 0.8676 | 1.4124 | |
| HCC38 | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 6.67 | uM | 7468.073 | 0.7141 | 0.5758 | 1.4124 | |
| HCC38 | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 33.3 | uM | 7468.073 | 0.1672 | -0.4364 | 1.4124 |