Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-361 | HER2amp | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 0.0533 | uM | 7894.016 | 0.9629 | 0.9047 | 0.7753 | ||
| MDA-MB-361 | HER2amp | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 0.267 | uM | 7894.016 | 0.9727 | 0.9299 | 0.7753 | ||
| MDA-MB-361 | HER2amp | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 1.33 | uM | 7894.016 | 0.9487 | 0.8687 | 0.7753 | ||
| MDA-MB-361 | HER2amp | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 6.67 | uM | 7894.016 | 0.8439 | 0.6067 | 0.7753 | ||
| MDA-MB-361 | HER2amp | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 33.3 | uM | 7894.016 | 0.8962 | 0.7362 | 0.7753 | ||
| MDA-MB-361 | HER2amp | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 167 | uM | 7894.016 | 0.8851 | 0.7087 | 0.7753 | ||
| MDA-MB-361 | HER2amp | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 0.000427 | uM | 7895.016 | 1.0454 | 1.0696 | 1.2977 | ||
| MDA-MB-361 | HER2amp | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 0.00213 | uM | 7895.016 | 0.9478 | 0.9191 | 1.2977 | ||
| MDA-MB-361 | HER2amp | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 0.0107 | uM | 7895.016 | 0.9256 | 0.8842 | 1.2977 | ||
| MDA-MB-361 | HER2amp | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 0.0533 | uM | 7895.016 | 0.8928 | 0.8326 | 1.2977 | ||
| MDA-MB-361 | HER2amp | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 0.267 | uM | 7895.016 | 0.9195 | 0.8747 | 1.2977 | ||
| MDA-MB-361 | HER2amp | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 1.33 | uM | 7895.016 | 0.9523 | 0.9260 | 1.2977 | ||
| MDA-MB-361 | HER2amp | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 6.67 | uM | 7895.016 | 0.9329 | 0.8957 | 1.2977 | ||
| MDA-MB-361 | HER2amp | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 33.3 | uM | 7895.016 | 0.7904 | 0.6684 | 1.2977 | ||
| MDA-MB-361 | HER2amp | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 167 | uM | 7895.016 | 0.6790 | 0.4841 | 1.2977 | ||
| MDA-MB-361 | HER2amp | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 0.000427 | uM | 7896.016 | 1.0344 | 1.0775 | 0.8912 | ||
| MDA-MB-361 | HER2amp | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 0.00213 | uM | 7896.016 | 0.9551 | 0.8996 | 0.8912 | ||
| MDA-MB-361 | HER2amp | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 0.0107 | uM | 7896.016 | 0.9718 | 0.9368 | 0.8912 | ||
| MDA-MB-361 | HER2amp | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 0.0533 | uM | 7896.016 | 0.9645 | 0.9206 | 0.8912 | ||
| MDA-MB-361 | HER2amp | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 0.267 | uM | 7896.016 | 0.9721 | 0.9375 | 0.8912 | ||
| MDA-MB-361 | HER2amp | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 1.33 | uM | 7896.016 | 0.9698 | 0.9323 | 0.8912 | ||
| MDA-MB-361 | HER2amp | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 6.67 | uM | 7896.016 | 0.9667 | 0.9254 | 0.8912 | ||
| MDA-MB-361 | HER2amp | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 33.3 | uM | 7896.016 | 0.7718 | 0.4955 | 0.8912 | ||
| MDA-MB-361 | HER2amp | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 167 | uM | 7896.016 | 0.9032 | 0.7842 | 0.8912 | ||
| MDA-MB-361 | HER2amp | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 0.000427 | uM | 9648.132 | 0.9911 | 0.9751 | 0.7147 |