Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UACC-893 | HER2amp | Luminal | AG1478 | EGFR | ErbB | 0.00213 | uM | 9045.016 | 0.9459 | 0.8805 | 0.9026 | |
| UACC-893 | HER2amp | Luminal | AG1478 | EGFR | ErbB | 0.0107 | uM | 9045.016 | 1.1143 | 1.2547 | 0.9026 | |
| UACC-893 | HER2amp | Luminal | AG1478 | EGFR | ErbB | 0.0533 | uM | 9045.016 | 0.8486 | 0.6675 | 0.9026 | |
| UACC-893 | HER2amp | Luminal | AG1478 | EGFR | ErbB | 0.267 | uM | 9045.016 | 1.0294 | 1.0652 | 0.9026 | |
| UACC-893 | HER2amp | Luminal | AG1478 | EGFR | ErbB | 1.33 | uM | 9045.016 | 0.9055 | 0.7916 | 0.9026 | |
| UACC-893 | HER2amp | Luminal | AG1478 | EGFR | ErbB | 6.67 | uM | 9045.016 | 0.6728 | 0.2892 | 0.9026 | |
| UACC-893 | HER2amp | Luminal | AG1478 | EGFR | ErbB | 33.3 | uM | 9045.016 | 0.0988 | -0.8460 | 0.9026 | |
| UACC-893 | HER2amp | Luminal | AG1478 | EGFR | ErbB | 167 | uM | 9045.016 | 0.0371 | -0.9480 | 0.9026 | |
| ZR-75-1 | HR+ | Luminal | AG1478 | EGFR | ErbB | 0.000427 | uM | 7931.016 | 1.0366 | 1.0554 | 1.3152 | |
| ZR-75-1 | HR+ | Luminal | AG1478 | EGFR | ErbB | 0.00213 | uM | 7931.016 | 0.9233 | 0.8822 | 1.3152 | |
| ZR-75-1 | HR+ | Luminal | AG1478 | EGFR | ErbB | 0.0107 | uM | 7931.016 | 1.0044 | 1.0067 | 1.3152 | |
| ZR-75-1 | HR+ | Luminal | AG1478 | EGFR | ErbB | 0.0533 | uM | 7931.016 | 0.9719 | 0.9572 | 1.3152 | |
| ZR-75-1 | HR+ | Luminal | AG1478 | EGFR | ErbB | 0.267 | uM | 7931.016 | 0.9928 | 0.9890 | 1.3152 | |
| ZR-75-1 | HR+ | Luminal | AG1478 | EGFR | ErbB | 1.33 | uM | 7931.016 | 0.9367 | 0.9029 | 1.3152 | |
| ZR-75-1 | HR+ | Luminal | AG1478 | EGFR | ErbB | 6.67 | uM | 7931.016 | 0.8759 | 0.8083 | 1.3152 | |
| ZR-75-1 | HR+ | Luminal | AG1478 | EGFR | ErbB | 33.3 | uM | 7931.016 | 0.9034 | 0.8514 | 1.3152 | |
| ZR-75-1 | HR+ | Luminal | AG1478 | EGFR | ErbB | 167 | uM | 7931.016 | 0.7632 | 0.6286 | 1.3152 | |
| ZR-75-1 | HR+ | Luminal | AG1478 | EGFR | ErbB | 0.000427 | uM | 7932.016 | 1.0910 | 1.2894 | 0.6446 | |
| ZR-75-1 | HR+ | Luminal | AG1478 | EGFR | ErbB | 0.00213 | uM | 7932.016 | 1.0139 | 1.0431 | 0.6446 | |
| ZR-75-1 | HR+ | Luminal | AG1478 | EGFR | ErbB | 0.0107 | uM | 7932.016 | 1.1337 | 1.4298 | 0.6446 | |
| ZR-75-1 | HR+ | Luminal | AG1478 | EGFR | ErbB | 0.0533 | uM | 7932.016 | 0.9462 | 0.8356 | 0.6446 | |
| ZR-75-1 | HR+ | Luminal | AG1478 | EGFR | ErbB | 0.267 | uM | 7932.016 | 1.0053 | 1.0164 | 0.6446 | |
| ZR-75-1 | HR+ | Luminal | AG1478 | EGFR | ErbB | 1.33 | uM | 7932.016 | 0.9782 | 0.9329 | 0.6446 | |
| ZR-75-1 | HR+ | Luminal | AG1478 | EGFR | ErbB | 6.67 | uM | 7932.016 | 1.0248 | 1.0775 | 0.6446 | |
| ZR-75-1 | HR+ | Luminal | AG1478 | EGFR | ErbB | 33.3 | uM | 7932.016 | 1.0313 | 1.0980 | 0.6446 |