Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM52PE | HR+ | Luminal | PS-1145 | IKK | NFKB | 0.00485 | uM | 7541.065 | 1.0742 | 1.1076 | 1.3660 | |
| SUM52PE | HR+ | Luminal | PS-1145 | IKK | NFKB | 0.0243 | uM | 7541.065 | 1.0632 | 1.0917 | 1.3660 | |
| SUM52PE | HR+ | Luminal | PS-1145 | IKK | NFKB | 0.121 | uM | 7541.065 | 0.9060 | 0.8606 | 1.3660 | |
| SUM52PE | HR+ | Luminal | PS-1145 | IKK | NFKB | 0.606 | uM | 7541.065 | 1.1495 | 1.2148 | 1.3660 | |
| SUM52PE | HR+ | Luminal | PS-1145 | IKK | NFKB | 3.03 | uM | 7541.065 | 1.1222 | 1.1761 | 1.3660 | |
| SUM52PE | HR+ | Luminal | PS-1145 | IKK | NFKB | 15.2 | uM | 7541.065 | 0.9824 | 0.9742 | 1.3660 | |
| SUM52PE | HR+ | Luminal | PS-1145 | IKK | NFKB | 75.8 | uM | 7541.065 | 0.9865 | 0.9802 | 1.3660 | |
| SUM52PE | HR+ | Luminal | PS-1145 | IKK | NFKB | 379 | uM | 7541.065 | 0.9859 | 0.9793 | 1.3660 | |
| SUM52PE | HR+ | Luminal | PS-1145 | IKK | NFKB | 1890 | uM | 7541.065 | 0.9759 | 0.9647 | 1.3660 | |
| T47D | HR+ | Luminal | PS-1145 | IKK | NFKB | 0.00485 | uM | 7542.065 | 1.0230 | 1.0371 | 1.2381 | |
| T47D | HR+ | Luminal | PS-1145 | IKK | NFKB | 0.0243 | uM | 7542.065 | 1.0123 | 1.0199 | 1.2381 | |
| T47D | HR+ | Luminal | PS-1145 | IKK | NFKB | 0.121 | uM | 7542.065 | 0.9984 | 0.9975 | 1.2381 | |
| T47D | HR+ | Luminal | PS-1145 | IKK | NFKB | 0.606 | uM | 7542.065 | 1.0131 | 1.0212 | 1.2381 | |
| T47D | HR+ | Luminal | PS-1145 | IKK | NFKB | 3.03 | uM | 7542.065 | 0.9988 | 0.9981 | 1.2381 | |
| T47D | HR+ | Luminal | PS-1145 | IKK | NFKB | 15.2 | uM | 7542.065 | 1.0022 | 1.0035 | 1.2381 | |
| T47D | HR+ | Luminal | PS-1145 | IKK | NFKB | 75.8 | uM | 7542.065 | 0.9987 | 0.9979 | 1.2381 | |
| T47D | HR+ | Luminal | PS-1145 | IKK | NFKB | 379 | uM | 7542.065 | 0.9777 | 0.9639 | 1.2381 | |
| T47D | HR+ | Luminal | PS-1145 | IKK | NFKB | 1890 | uM | 7542.065 | 0.9334 | 0.8917 | 1.2381 | |
| T47D | HR+ | Luminal | PS-1145 | IKK | NFKB | 0.00485 | uM | 7543.065 | 0.9406 | 0.9060 | 1.2714 | |
| T47D | HR+ | Luminal | PS-1145 | IKK | NFKB | 0.0243 | uM | 7543.065 | 0.9716 | 0.9552 | 1.2714 | |
| T47D | HR+ | Luminal | PS-1145 | IKK | NFKB | 0.121 | uM | 7543.065 | 0.9725 | 0.9566 | 1.2714 | |
| T47D | HR+ | Luminal | PS-1145 | IKK | NFKB | 0.606 | uM | 7543.065 | 0.9795 | 0.9677 | 1.2714 | |
| T47D | HR+ | Luminal | PS-1145 | IKK | NFKB | 3.03 | uM | 7543.065 | 0.9639 | 0.9429 | 1.2714 | |
| T47D | HR+ | Luminal | PS-1145 | IKK | NFKB | 15.2 | uM | 7543.065 | 0.9801 | 0.9686 | 1.2714 | |
| T47D | HR+ | Luminal | PS-1145 | IKK | NFKB | 75.8 | uM | 7543.065 | 0.9696 | 0.9521 | 1.2714 |